FAM33A 抗体 (N-Term)
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- 抗原 See all FAM33A 抗体
- FAM33A (Spindle and Kinetochore-Associated Protein 2 (FAM33A))
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抗原表位
- N-Term
- 适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FAM33A antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB)
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- 15 amino acid peptide from near the amino terminus of human SKA2.
- Top Product
- Discover our top product FAM33A Primary Antibody
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anti-Spindle and Kinetochore-Associated Protein 2 (FAM33A) (AA 1-121) antibody
FAM33A 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Spindle and Kinetochore-Associated Protein 2 (FAM33A) (N-Term) antibodyFAM33A 适用: 人, 小鼠 ELISA, WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Spindle and Kinetochore-Associated Protein 2 (FAM33A) (AA 9-37), (N-Term) antibodyFAM33A 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB31468 unconjugated
anti-Spindle and Kinetochore-Associated Protein 2 (FAM33A) (AA 16-45), (N-Term) antibodyFAM33A 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
- 注意事项
- Avoid freezing and thawing repeatly.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 4 °C for short term use.Store at -20 °C for long term preservation.
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- 抗原
- FAM33A (Spindle and Kinetochore-Associated Protein 2 (FAM33A))
- 别名
- SKA2 (FAM33A 产品)
- 别名
- FAM33A antibody, 1110001A07Rik antibody, C78640 antibody, Fam33a antibody, RGD1307084 antibody, fam33a antibody, spindle and kinetochore associated complex subunit 2 antibody, Spindle and kinetochore-associated protein 2 antibody, SKA2 antibody, Ska2 antibody, ska2 antibody
- 背景
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Upon entry into mitosis, the cell's microtubule (MT) network forms the mitotic spindle, allowing the segregation of paired chromosomes.Proteinaceous structures on centromeric chromatin termed kinetochores (KT) are essential for the proper attachment of the chromosomes to the spindle MTs.A recently discovered spindle and kinetochore complex, comprised of proteins SKA1, SKA2, and SKA3, has been found to be required for stable KT-MT interactions and timely anaphase onset.Depletion of either SKA1 or SKA2 by siRNA results in the loss of both proteins from the KT, but does not impact overall KT structure.Cells depleted of the SKA complex undergo a prolonged checkpoint-dependent delay in a metaphase-like state, indicating the importance of the SKA complex in the maintenance of the metaphase plate and spindle checkpoint silencing.SKA2 has also been shown to interact with glucocorticoid receptors and to be involved in glucocorticoid signaling and cell proliferation.
Synonyms: Spindle and kinetochore associated complex subunit 2, FAM33A - NCBI登录号
- NP_872426
- 途径
- M Phase
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