FRMPD2 抗体 (N-Term)
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- 抗原 See all FRMPD2 抗体
- FRMPD2 (FERM and PDZ Domain Containing 2 (FRMPD2))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FRMPD2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- 15 amino acid peptide from near the amino terminus of human FRMPD2.
- Top Product
- Discover our top product FRMPD2 Primary Antibody
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anti-FERM and PDZ Domain Containing 2 (FRMPD2) (AA 1-261) antibody
FRMPD2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-FERM and PDZ Domain Containing 2 (FRMPD2) (N-Term) antibodyFRMPD2 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-FERM and PDZ Domain Containing 2 (FRMPD2) (N-Term) antibodyFRMPD2 适用: 人, Cow, 豚鼠, 马, Pig WB 宿主: 兔 Polyclonal unconjugated
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
- 注意事项
- Avoid freezing and thawing repeatly.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 4 °C for short term use.Store at -20 °C for long term preservation.
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- 抗原
- FRMPD2 (FERM and PDZ Domain Containing 2 (FRMPD2))
- 别名
- FRMPD2 (FRMPD2 产品)
- 别名
- Frmpd2 antibody, Gm1582 antibody, ENSMUSG00000071536 antibody, FRMPD2 antibody, PDZD5C antibody, PDZK4 antibody, PDZK5C antibody, FERM and PDZ domain containing 2 antibody, putative protein FRMPD2-like antibody, FERM and PDZ domain-containing protein 2 antibody, Frmpd2 antibody, FRMPD2 antibody, LOC100051923 antibody, LOC100348282 antibody, LOC100548446 antibody
- 背景
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The FERM and PDZ domain containing (FRMPD) protein family consists of four proteins that contain a FERM (Four-point-one, erzin, radixin, moesin) domain and at least one PDZ (PSD-95/Discs large/Zonula-occuldens-1) domain.FRMPD2 also contains an N-terminal KIND domain and three PDZ domains and is structurally similar to the protein tyrosine phosphatase PTP-BL.FRMPD2 is localized in a polarized fashion in epithelial cells at the basolateral membrane and partially co-localizes with the tight-junction marker protein Zonula-occuldens-1.Suppression of FRMPD2 expression via RNAi in Caco-2 cells results in an impairment of tight junction formation, indicating that FRMPD2 plays a major role in tight junction formation.Other experiments indicate that FRMPD2 is a binding partner to several catenin family members and recruitment of FRMPD2 to cell-cell contacts is dependent on E-cadherin-mediated cell-cell adhesion.
Synonyms: FERM and PDZ domain-containing 2, PDZD5C, PDZK5C - NCBI登录号
- NP_001018081
- 途径
- Cell-Cell Junction Organization
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