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SKI 抗体 (N-Term)

SKI 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1887862
发货至: 中国
  • 抗原 See all SKI 抗体
    SKI (SKI Proto-Oncogene (SKI))
    抗原表位
    • 7
    • 4
    • 1
    • 1
    • 1
    N-Term
    适用
    • 26
    • 20
    • 11
    • 3
    • 3
    宿主
    • 23
    • 3
    克隆类型
    • 23
    • 3
    多克隆
    标记
    • 12
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This SKI antibody is un-conjugated
    应用范围
    • 10
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    14 amino acid peptide from near the amino terminus of human Ski.
    Top Product
    Discover our top product SKI Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    注意事项
    Avoid freezing and thawing repeatly.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 4 °C for short term use.Store at -20 °C for long term preservation.
  • 抗原
    SKI (SKI Proto-Oncogene (SKI))
    别名
    Ski (SKI 产品)
    别名
    SGS antibody, SKV antibody, SKI antibody, C-SKI antibody, RGD1565591 antibody, c-ski antibody, 2310012I02Rik antibody, 2610001A11Rik antibody, AA062172 antibody, AA589460 antibody, BC004088 antibody, ski antibody, skv antibody, xski antibody, id:ibd1250 antibody, SKI proto-oncogene antibody, ski sarcoma viral oncogene homolog (avian) antibody, SKI proto-oncogene L homeolog antibody, v-ski avian sarcoma viral oncogene homolog a antibody, SKI antibody, Ski antibody, ski.L antibody, skia antibody
    背景
    TGF-beta is a ubiquitously expressed cytokine that signals through the Smad protein family to regulate numerous cellular processes such as embryonic development and tumorigenesis.This signaling is negatively regulated by Ski, the mammalian homolog of the transforming protein of an avian retrovirus that induces oncogenic transformation of chicken embryo cells, and the related protein SnoN.Ski functions by binding to the Smad proteins and preventing their phosphorylation, thereby inhibiting their ability to bind DNA and activate the transcription of downstream genes.Ski will also bind to the Smad proteins specific to bone morphogenic proteins (BMPs) and block BMP signaling in mammalian cells.
    Synonyms: c-ski, v-ski sarcoma viral oncogene homolog
    UniProt
    P12755
    途径
    Stem Cell Maintenance, Tube Formation, Skeletal Muscle Fiber Development
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