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BAG1 抗体 (N-Term)

BAG1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1887852
发货至: 中国
  • 抗原 See all BAG1 抗体
    BAG1 (BCL2-Associated Athanogene (BAG1))
    抗原表位
    • 4
    • 3
    • 3
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    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    N-Term
    适用
    • 33
    • 19
    • 17
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 30
    • 8
    克隆类型
    • 30
    • 8
    多克隆
    标记
    • 31
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BAG1 antibody is un-conjugated
    应用范围
    • 30
    • 14
    • 11
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    • 9
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
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    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    14 amino acid peptide from near the amino terminus of human BAG-1.
    Top Product
    Discover our top product BAG1 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    注意事项
    Avoid freezing and thawing repeatly.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 4 °C for short term use.Store at -20 °C for long term preservation.
  • 抗原
    BAG1 (BCL2-Associated Athanogene (BAG1))
    别名
    BAG-1 (BAG1 产品)
    别名
    BAG-1 antibody, HAP antibody, RAP46 antibody, Rap46 antibody, Bag-1 antibody, ATBAG1 antibody, BCL-2-associated athanogene 1 antibody, MSG15.15 antibody, MSG15_15 antibody, im:7148830 antibody, si:dkey-216e9.4 antibody, BCL2 associated athanogene 1 antibody, putative bcl2-associated athanogene antibody, BCL2-associated athanogene 1 antibody, Bcl2 associated athanogene 1 antibody, BAG family molecular chaperone regulator 1 antibody, BCL-2-associated athanogene 1 antibody, BAG1 antibody, Smp_005900 antibody, Bag1 antibody, bag-1 antibody, LOC781741 antibody, bag1 antibody
    背景
    Bcl-2-associated athanogene 1 (BAG-1) was first identified as an anti-apoptotic bcl-2-binding protein.Later it was found to bind the molecular chaperones Hsp70 and Hsc70 through its carboxy-terminal sequence (termed the Bag domain), resulting in the inhibition of the refolding activity of these chaperones.It is thought that by binding and inhibiting these molecular chaperones, BAG-1is able to modulate the expression level of proteins requiring chaperones to fold correctly.One such group of proteins that are affected is glucocorticoid receptors.Other reports have suggested that the level of BAG-1 expression correlates with the aggressiveness of various cancers.Multiple isoforms of BAG-1 are known to exist.
    Synonyms: Bcl-2-binding athanogene-1, receptor-associated protein 46, RAP46
    NCBI登录号
    NP_004314
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