RNASEH2A 抗体 (Center)
-
- 抗原 See all RNASEH2A 抗体
- RNASEH2A (Ribonuclease H2, Subunit A (RNASEH2A))
-
抗原表位
- Center
-
适用
- 人, 大鼠, 小鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This RNASEH2A antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- 17 amino acid peptide near the center of human RNAse H2A.
- Top Product
- Discover our top product RNASEH2A Primary Antibody
-
anti-Ribonuclease H2, Subunit A (RNASEH2A) (AA 1-299) antibody
RNASEH2A 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 3G5-F5 unconjugated
anti-Ribonuclease H2, Subunit A (RNASEH2A) (AA 1-299) antibodyRNASEH2A 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Ribonuclease H2, Subunit A (RNASEH2A) (AA 1-301) antibodyRNASEH2A 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ribonuclease H2, Subunit A (RNASEH2A) (C-Term) antibodyRNASEH2A 适用: 人, 斑马鱼, Pig, Cow, 马, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ribonuclease H2, Subunit A (RNASEH2A) (AA 1-299) antibodyRNASEH2A 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Ribonuclease H2, Subunit A (RNASEH2A) (AA 1-299) antibodyRNASEH2A 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ribonuclease H2, Subunit A (RNASEH2A) (AA 1-301) antibodyRNASEH2A 适用: 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ribonuclease H2, Subunit A (RNASEH2A) (C-Term) antibodyRNASEH2A 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ribonuclease H2, Subunit A (RNASEH2A) (AA 201-299) antibodyRNASEH2A 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ribonuclease H2, Subunit A (RNASEH2A) (AA 1-299) antibodyRNASEH2A 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
-
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
- 注意事项
- Avoid freezing and thawing repeatly.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 4 °C for short term use.Store at -20 °C for long term preservation.
-
- 抗原
- RNASEH2A (Ribonuclease H2, Subunit A (RNASEH2A))
- 别名
- RNAse H2A (RNASEH2A 产品)
- 别名
- 2400006P09Rik antibody, RNASEHI antibody, RNHIA antibody, RNHL antibody, zgc:56307 antibody, AGS4 antibody, JUNB antibody, ribonuclease H2 subunit A antibody, ribonuclease H2, large subunit antibody, ribonuclease H2, subunit A antibody, ribonuclease H2 subunit A L homeolog antibody, rnaseh2a antibody, RNASEH2A antibody, Rnaseh2a antibody, rnaseh2a.L antibody
- 背景
-
Ribonucleases (RNAses) H are enzymes that hydrolyze the RNA strands of RNA/DNA hybrids.The major role of these enzymes is to remove the RNA strand from the RNA/DNA hybrids that form during DNA replication and repair.RNAse H2 is made up of three subunits, all three are required for RNAse activity.Recent evidence has demonstrated that mutations in RNAse H2A or any of the other subunits result in Aicardi-Goutieres syndrome (AGS), a neurological disorder with similar symptoms to viral brain infections including high levels of IFN-alpha in the cerebral spinal fluid.Similar conditions are observed with mutations in TREX1, a single-stranded DNA exonuclease, suggesting that RNAse H2 and TREX1 may have similar roles, and that mutations in any of these genes lead to an accumulation of intracellular nucleic acids, triggering an inflammatory response through activation of the innate immune system.
Synonyms: Rnse H2A, Ribonuclease H2 subunit A, RNAse HI large subunit, Aicadi-Goutieres, syndrome 4 protein, AGS4 - UniProt
- O75792
-
