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GOPC 抗体 (Center)

GOPC 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1887642
发货至: 中国
  • 抗原 See all GOPC 抗体
    GOPC (Golgi-Associated PDZ and Coiled-Coil Motif Containing (GOPC))
    抗原表位
    • 15
    • 7
    • 7
    • 7
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    适用
    • 77
    • 33
    • 10
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    人, 小鼠
    宿主
    • 76
    • 1
    克隆类型
    • 68
    • 9
    多克隆
    标记
    • 29
    • 7
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GOPC antibody is un-conjugated
    应用范围
    • 39
    • 25
    • 25
    • 14
    • 14
    • 11
    • 8
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    17 amino acid peptide from near the center of human PIST.
    Top Product
    Discover our top product GOPC Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    注意事项
    Avoid freezing and thawing repeatly.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 4 °C for short term use.Store at -20 °C for long term preservation.
  • 抗原
    GOPC (Golgi-Associated PDZ and Coiled-Coil Motif Containing (GOPC))
    别名
    PIST (GOPC 产品)
    别名
    DKFZp459H2130 antibody, 2210402P09Rik antibody, AI844555 antibody, CAL antibody, FIG antibody, GOPC1 antibody, PIST antibody, fe38f01 antibody, wu:fe38f01 antibody, zgc:56254 antibody, zgc:65853 antibody, dJ94G16.2 antibody, cal antibody, gopc1 antibody, pist antibody, golgi associated PDZ and coiled-coil motif containing antibody, golgi-associated PDZ and coiled-coil motif containing antibody, golgi-associated PDZ and coiled-coil motif containing S homeolog antibody, GOPC antibody, Gopc antibody, gopc antibody, gopc.S antibody
    背景
    Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells.It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components and is negatively regulated by TOR (Target of rapamycin).PIST, a PDZ-containing protein, was discovered in a yeast two-hybrid system as a binding partner to Beclin-1, a Bcl-2-interacting protein homologous to the yeast autophagy gene apg6.Experiments with mutant PIST proteins lacking the PDZ domain showed that PIST interaction with Beclin-1 through its coiled-coil domain can modulate Beclin-1 activity and suggest that PIST interactions with other proteins through its PDZ domain may regulate the activity of PIST and Beclin-1.
    Synonyms: Golgi associated PDZ and coiled-coil motif containing, GOPC
    途径
    Maintenance of Protein Location, Asymmetric Protein Localization
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