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Syntaphilin 抗体 (Center)

SNPH 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1887607
发货至: 中国
  • 抗原 See all Syntaphilin (SNPH) 抗体
    Syntaphilin (SNPH)
    抗原表位
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    适用
    • 14
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 11
    • 3
    克隆类型
    • 13
    • 1
    多克隆
    标记
    • 10
    • 2
    • 1
    • 1
    This Syntaphilin antibody is un-conjugated
    应用范围
    • 9
    • 7
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    16 amino acid peptide from near the center of human Syntaphilin.
    Top Product
    Discover our top product SNPH Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    注意事项
    Avoid freezing and thawing repeatly.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 4 °C for short term use.Store at -20 °C for long term preservation.
  • 抗原
    Syntaphilin (SNPH)
    别名
    Syntaphilin (SNPH 产品)
    别名
    bA314N13.5 antibody, 6430515A01 antibody, AW045671 antibody, AW556958 antibody, AW743098 antibody, mKIAA0374 antibody, syntaphilin antibody, SNPH antibody, Snph antibody
    背景
    Syntaphilin was initially identified in a yeast two-hybrid screen with the carboxy terminal region of Syntaxin-1 as bait.Syntaxin-1 is a key component of the synaptic vesicle docking machinery that forms the SNARE complex with synaptobrevin and SNAP-25.Syntaphilin competes with SNAP-25 for binding to syntaxin-1 and inhibits the formation of the SNARE complex, thereby potentially regulating synaptic vesicle exocytosis.Syntaphilin also binds dynamin-1 and inhibits dynamin-dependent endocytosis.Mice lacking syntaphilin show an increased level of mitochondrial motility and a reduced density of axonal mitochondria.This correlates with an enhanced short-term facilitation and significant impairments in motor ability, suggesting syntaphilin plays a major role in presynaptic function.Multiple isoforms are known to exist.
    Synonyms: SNPH
    UniProt
    O15079
    途径
    Synaptic Vesicle Exocytosis
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