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RANBP10 抗体 (Center)

RANBP10 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1887563
发货至: 中国
  • 抗原 See all RANBP10 抗体
    RANBP10 (RAN Binding Protein 10 (RANBP10))
    抗原表位
    • 1
    • 1
    • 1
    Center
    适用
    • 4
    • 1
    • 1
    宿主
    • 4
    克隆类型
    • 4
    多克隆
    标记
    • 4
    This RANBP10 antibody is un-conjugated
    应用范围
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    15 amino acid peptide near the center of human RANBP10.
    Top Product
    Discover our top product RANBP10 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    注意事项
    Avoid freezing and thawing repeatly.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 4 °C for short term use.Store at -20 °C for long term preservation.
  • 抗原
    RANBP10 (RAN Binding Protein 10 (RANBP10))
    别名
    RANBP10 (RANBP10 产品)
    别名
    RGD1311587 antibody, 4432417N03Rik antibody, si:ch211-193l7.1 antibody, RAN binding protein 10 antibody, Ranbp10 antibody, RANBP10 antibody, ranbp10 antibody
    背景
    The RAN binding protein 10 (RANBP10) is a cytoplasmic guanine nucleotide exchange factor that shares high sequence similarity to the MET-interacting protein RANBP9.RANBP10 is expressed in the cytoplasm of mature megakaryocytes (MKs) and platelets where it localizes to polymerized noncentrosomal microtubules.RANBP10 possesses guanine nucleotide exchange factor activity towards RAN, a GTPase involved in nucleocytoplasmic traffic, spindle formation at mitosis, and nuclear envelope assembly during telophase, suggesting that RANBP10 may also be involved in these activities.RANBP10 depletion in vitro caused the disturbance of polymerized filaments in MKs and platelets in RANBP10-null mice exhibited disorders in microtubule filament numbers and localization, indicating that RANBP10 may play a significant role in maintaining microtubule dynamics.
    Synonyms: RAN binding protein 10
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