At least three isoforms of ZMYM3 are known to exist, this antibody will detect all three. ZMYM3 antibody is predicted to not cross-react with other ZMYM protein family members.
纯化方法
Affinity chromatography purified via peptide column
免疫原
20 amino acid peptide near the carboxy terminus of human AXIN2.
WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
注意事项
Avoid freezing and thawing repeatly.
储存条件
4 °C/-20 °C
储存方法
Store at 4 °C for short term use.Store at -20 °C for long term preservation.
Zinc-finger proteins contain DNA-binding domains characterized by the unique role of zinc and have a wide variety of functions such as transcriptional activation or repression.The protein folding and the DNA binding ability are governed by the coordination of a zinc ion.As a member of the MYM (myeloproliferative and mental retardation) gene family, ZMYM3 is highly conserved in vertebrates and most abundantly expressed in the brain.The encoded protein is a component of histone deacetylase-containing multiprotein complexes that function through modifying chromatin structure to keep genes silent.A chromosomal translocation (X,13) involving this gene is associated with X-linked mental retardation. Synonyms: Zinc finger MYM-type protein 3, ZNF261, ZNF198L2, XFIM, MYM