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FERMT3 抗体 (C-Term)

FERMT3 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1887294
发货至: 中国
  • 抗原 See all FERMT3 抗体
    FERMT3 (Fermitin Family Member 3 (FERMT3))
    抗原表位
    • 15
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    C-Term
    适用
    人, 小鼠, 大鼠
    宿主
    • 32
    • 4
    • 1
    • 1
    克隆类型
    • 36
    • 2
    多克隆
    标记
    • 20
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FERMT3 antibody is un-conjugated
    应用范围
    • 17
    • 13
    • 13
    • 11
    • 7
    • 7
    • 6
    • 3
    • 3
    • 1
    Western Blotting (WB), ELISA
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    19 amino acid peptide near the carboxy terminus of the human KINDLIN3.
    Top Product
    Discover our top product FERMT3 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    注意事项
    Avoid freezing and thawing repeatly.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 4 °C for short term use.Store at -20 °C for long term preservation.
  • 抗原
    FERMT3 (Fermitin Family Member 3 (FERMT3))
    别名
    KINDLIN3 (FERMT3 产品)
    别名
    C79673 antibody, Kindlin3 antibody, RGD1310168 antibody, MGC69069 antibody, MGC88900 antibody, KIND3 antibody, MIG-2 antibody, MIG2B antibody, UNC112C antibody, URP2 antibody, URP2SF antibody, zgc:64101 antibody, fermitin family member 3 antibody, fermitin family member 3 L homeolog antibody, fermitin family member 3b antibody, Fermt3 antibody, fermt3.L antibody, fermt3 antibody, FERMT3 antibody, fermt3b antibody
    背景
    The three KINDLINs are a novel family of focal adhesion proteins, localizing to integrin adhesion sites.The KINDLIN proteins are composed of a centrally located FERM domain interrupted by a pleckstrin homology (PH) domain.KINDLIN1 and KINDLIN2 have been shown to play an essential role in integrin-mediated adhesion and spreading.In contrast to the widely expressed KINDLIN1 and KINDLIN2, KINDLIN3 is restricted to hematopoietic cells and is particularly abundant in megakaryocytes and platelets.Several reports describe a transcriptional misregulation of KINDLINs in various types of cancer.A recent study demonstrates that KINDLIN3 is essential for platelet integrin activation and subsequent integrin outside-in signaling, suggesting it may serve as a potential target for the design of therapeutics aimed at specifically disrupting integrin activation in platelets and leukocytes.
    Synonyms: Fermitin family homolog 3, FERMT, Unc-112-related protein 2, MIG2-like protein, KIND3, MIG2B, URP2
    NCBI登录号
    NP_848537
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