LRRTM3 抗体 (C-Term)
LRRTM3
适用: 小鼠, 人, 大鼠
WB, ELISA, IHC
宿主: 兔
Polyclonal
unconjugated
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- 抗原 See all LRRTM3 抗体
- LRRTM3 (Leucine Rich Repeat Transmembrane Neuronal 3 (LRRTM3))
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抗原表位
- C-Term
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适用
- 小鼠, 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This LRRTM3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 特异性
- At least two isoforms of LRRTM3 are known to exist, this antibody will only detect the larger isoform.
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- 18 amino acid peptide near the carboxy terminus of human LRRTM3.
- Top Product
- Discover our top product LRRTM3 Primary Antibody
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
- 注意事项
- Avoid freezing and thawing repeatly.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 4 °C for short term use.Store at -20 °C for long term preservation.
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- 抗原
- LRRTM3 (Leucine Rich Repeat Transmembrane Neuronal 3 (LRRTM3))
- 别名
- LRRTM3 (LRRTM3 产品)
- 别名
- 9630044H04Rik antibody, leucine rich repeat transmembrane neuronal 3 antibody, LRRTM3 antibody, lrrtm3 antibody, Lrrtm3 antibody
- 背景
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The Leucine-rich repeat transmembrane neuronal proteins (LRRTMs) are differentially expressed in the nervous system and were recently found to instruct presynaptic and mediate postsynaptic glutamatergic differentiation, with LRRTM1 and LRRTM2 most potent at inducing presynaptic differentiation.Recent evidence suggests that LRRTM3 promotes the processing of amyloid-precursor protein (APP) by the beta-secretase BACE, leading to the proteolytic production of the Abeta42 peptide that is the main component of amyloid plaques.Furthermore, LRRTM3 maps to a region of chromosome 10 linked to both late-onset Alzheimer's disease (AD) and elevated plasma Abeta42 levels, suggesting that LRRTM3 is a functional and positional candidate gene for AD.
Synonyms: Leucine-rich repeat transmembrane neuronal protein 3 - NCBI登录号
- NP_821079
- 途径
- Synaptic Membrane
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