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STEAP1 抗体 (C-Term)

STEAP1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1887239
发货至: 中国
  • 抗原 See all STEAP1 抗体
    STEAP1 (Six Transmembrane Epithelial Antigen of The Prostate 1 (STEAP1))
    抗原表位
    • 15
    • 8
    • 5
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 45
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 41
    • 3
    • 1
    克隆类型
    • 43
    • 2
    多克隆
    标记
    • 20
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This STEAP1 antibody is un-conjugated
    应用范围
    • 42
    • 24
    • 15
    • 13
    • 13
    • 8
    • 4
    • 3
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    交叉反应 (详细)
    This STEAP1 antibody does not cross-react with other STEAP proteins.
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    18 amino acid peptide from near the carboxy terminus of human STEAP1.
    Top Product
    Discover our top product STEAP1 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    注意事项
    Avoid freezing and thawing repeatly.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 4 °C for short term use.Store at -20 °C for long term preservation.
  • 抗原
    STEAP1 (Six Transmembrane Epithelial Antigen of The Prostate 1 (STEAP1))
    别名
    STEAP1 (STEAP1 产品)
    别名
    PRSS24 antibody, STEAP antibody, STEAP1 antibody, 2410007B19Rik antibody, Prss24 antibody, Steap antibody, STEAP family member 1 antibody, six transmembrane epithelial antigen of the prostate 1 antibody, STEAP1 antibody, Steap1 antibody
    背景
    The six-transmembrane epithelial antigen of prostate 1 (STEAP1) was the first member of a family of metalloreductases identified as cell-surface antigens in prostate tissue.The normal function of STEAP is still uncertain, unlike other members of the STEAP family, STEAP1 does not promote iron or copper reduction or uptake and lacks the FNO-like reductase domain critical for activity.However, its expression is highly increased in multiple cancer cell lines, including prostate, bladder, colon, and ovarian cancers.Supporting this is evidence that STEAP1 peptides can be used to stimulate CD8+ T cells from healthy donors, enabling them to recognize STEAP1-positive human tumor cells, suggesting that STEAP1 may a potential target for cancer immunotherapy.At least three isoforms of STEAP1 are known to exist.
    Synonyms: Six transmembrane epithelial antigen of prostate 1, STEAP
    途径
    Transition Metal Ion Homeostasis
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