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NUMB 抗体 (C-Term)

NUMB 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1887202
发货至: 中国
  • 抗原 See all NUMB 抗体
    NUMB (Numb Homolog (NUMB))
    抗原表位
    • 15
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 53
    • 44
    • 17
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 58
    • 8
    • 2
    • 1
    克隆类型
    • 54
    • 15
    多克隆
    标记
    • 41
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NUMB antibody is un-conjugated
    应用范围
    • 53
    • 16
    • 16
    • 14
    • 13
    • 9
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    特异性
    At least four isoforms of NUMB are known to exist, this antibody will detect all of them.
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    17 amino acid peptide near the carboxy terminus of human NUMB.
    Top Product
    Discover our top product NUMB Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    注意事项
    Avoid freezing and thawing repeatly.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 4 °C for short term use.Store at -20 °C for long term preservation.
  • 抗原
    NUMB (Numb Homolog (NUMB))
    别名
    NUMB (NUMB 产品)
    别名
    C14orf41 antibody, S171 antibody, c14_5527 antibody, Nb antibody, NUMB, endocytic adaptor protein antibody, numb homolog (Drosophila) antibody, NUMB antibody, Numb antibody, numb antibody
    背景
    NUMB, the mammalian homolog to the Drosophila asymmetric cell fate determinant NUMB, is thought to share several features molecular mechanisms in mammalian cells, generating asymmetric cell divisions during neurogenesis in vertebrate development as well as in hematopoietic stem cells.NUMB has been shown to inhibit Notch signaling, and is itself regulated by ubiquitinylation by MDM2.NUMB has also been shown to help activate the tumor suppressor p53, suggesting that loss of NUMB in cancerous cells would not only activate the potential oncogene Notch, but diminish the tumor suppressing effect of p53.
    Synonyms: m-NUMB, S171
    NCBI登录号
    NP_1005743
    途径
    Cell-Cell Junction Organization
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