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TMEM38B 抗体 (C-Term)

TMEM38B 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1887180
发货至: 中国
  • 抗原 See all TMEM38B 抗体
    TMEM38B (Transmembrane Protein 38B (TMEM38B))
    抗原表位
    • 6
    • 3
    • 1
    • 1
    • 1
    C-Term
    适用
    • 10
    • 4
    • 3
    • 1
    人, 小鼠, 大鼠
    宿主
    • 10
    克隆类型
    • 10
    多克隆
    标记
    • 6
    • 2
    • 1
    • 1
    This TMEM38B antibody is un-conjugated
    应用范围
    • 6
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    17 amino acid peptide from near the carboxy terminus of human TMEM38B.
    Top Product
    Discover our top product TMEM38B Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    注意事项
    Avoid freezing and thawing repeatly.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 4 °C for short term use.Store at -20 °C for long term preservation.
  • 抗原
    TMEM38B (Transmembrane Protein 38B (TMEM38B))
    别名
    TMEM38B (TMEM38B 产品)
    别名
    zgc:55815 antibody, tricb antibody, tric-b antibody, MGC83592 antibody, DKFZp469C0220 antibody, C9orf87 antibody, D4Ertd89e antibody, OI14 antibody, TRIC-B antibody, TRICB antibody, bA219P18.1 antibody, 1600017F22Rik antibody, AA437809 antibody, AV051057 antibody, mg33b antibody, RGD1305703 antibody, transmembrane protein 38B antibody, transmembrane protein 38B L homeolog antibody, tmem38b antibody, TMEM38B antibody, tmem38b.L antibody, Tmem38b antibody
    背景
    TMEM38A and TMEM38B are two recently identified trimeric intracellular cation (TRIC) channel subtypes.TMEM38B is expressed in most mammalian tissues, while TMEM38A is preferentially expressed in excitable tissues such as striated muscle and brain.Mice deficient in both TMEM38A and TMEM38B suffer embryonic cardiac failure, the cardiac myocytes display severe dysfunction in SR Ca2+ handling, weakened Ca2+ release, and reduced K+ permeability indicating that the TRIC cation channels are likely to act as counter-ion channels that function in synchronization with Ca2+ release from intracellular stores.Mice that were lacking only TMEM38B however, die shortly after birth due to respiratory failure and have lungs exhibiting severe histological defect and ultrastructural abnormalities in their alveolar type II epithelial cells, indicating that TMEM38B are essential for perinatal lung maturation.Other experiments have shown that TMEM38A and TMEM38B can act with junctophilin proteins to support efficient ryanodine receptor-mediated Ca2+ release in muscle cells.
    Synonyms: Transmembrane protein 38B, TRIC-B, TRICB, trimeric cation channel type B
    NCBI登录号
    NP_060582
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