SPINK7/ECRG2 抗体 (C-Term)
-
- 抗原 See all SPINK7/ECRG2 (SPINK7) 抗体
- SPINK7/ECRG2 (SPINK7) (Serine Peptidase Inhibitor, Kazal Type 7 (SPINK7))
-
抗原表位
- C-Term
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This SPINK7/ECRG2 antibody is un-conjugated
-
应用范围
- ELISA, Western Blotting (WB)
- 交叉反应 （详细）
- ECRG2 antibody is predicted to not cross-react with other ECRG family members
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- 16 amino acid peptide near the carboxy terminus of human ECRG2.
- Top Product
- Discover our top product SPINK7 Primary Antibody
-
anti-Serine Peptidase Inhibitor, Kazal Type 7 (SPINK7) (AA 51-85) antibody
SPINK7 适用: 人, 小鼠 ELISA, WB, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Serine Peptidase Inhibitor, Kazal Type 7 (SPINK7) antibodySPINK7 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Serine Peptidase Inhibitor, Kazal Type 7 (SPINK7) (C-Term) antibodySPINK7 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 小鸡 Polyclonal unconjugated
-
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
- 注意事项
- Avoid freezing and thawing repeatly.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 4 °C for short term use.Store at -20 °C for long term preservation.
-
- 抗原
- SPINK7/ECRG2 (SPINK7) (Serine Peptidase Inhibitor, Kazal Type 7 (SPINK7))
- 别名
- ECRG2 (SPINK7 产品)
- 别名
- Ecg2 antibody, Ecrg2 antibody, OM antibody, ECG2 antibody, ECRG2 antibody, EG408198 antibody, serine peptidase inhibitor, Kazal type 7 antibody, serine peptidase inhibitor, Kazal type 7 (putative) antibody, Spink7 antibody, SPIK7 antibody, SPINK7 antibody
- 背景
-
The esophageal cancer-susceptibility gene 2 (ECRG2), also known as SPINK7, is a novel tumor suppressor gene identified from the human esophagus.It interacts directly with metallothionein 2A and urokinase-type plasminogen activator (uPA), and downregulates the activity of uPA, leading to reduced cancer cell migration, invasion and metastasis.ECRG2 forms a complex with uPA and its receptor uPAR, modifying the dynamic association of uPAR with beta1 integrins and disrupting the Src/MAP kinase pathway that normally stimulates cell migration and invasion.ECRG2 may thus represent a novel therapeutic target for cancer.
Synonyms: Esophageal cancer-susceptibility gene 2 protein, ECG2, serine protease inhibitor Kazal-type 7, SPINK7
-
