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IFIH1 抗体 (C-Term)

IFIH1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1887106
发货至: 中国
  • 抗原 See all IFIH1 抗体
    IFIH1 (Interferon Induced with Helicase C Domain 1 (IFIH1))
    抗原表位
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 42
    • 14
    • 4
    • 2
    • 2
    • 2
    • 1
    人, 小鼠
    宿主
    • 34
    • 8
    • 2
    克隆类型
    • 35
    • 9
    多克隆
    标记
    • 33
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IFIH1 antibody is un-conjugated
    应用范围
    • 29
    • 17
    • 14
    • 9
    • 7
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    16 amino acid peptide from near the carboxy terminus of human MDA5.
    Top Product
    Discover our top product IFIH1 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    注意事项
    Avoid freezing and thawing repeatly.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 4 °C for short term use.Store at -20 °C for long term preservation.
  • 抗原
    IFIH1 (Interferon Induced with Helicase C Domain 1 (IFIH1))
    别名
    MDA5 (IFIH1 产品)
    别名
    MDA5 antibody, Hlcd antibody, IDDM19 antibody, MDA-5 antibody, RLR-2 antibody, 9130009C22Rik antibody, Helicard antibody, RGD1560496 antibody, interferon induced with helicase C domain 1 antibody, IFIH1 antibody, Ifih1 antibody
    背景
    The innate immune system detects viral infection by recognizing various viral components and triggers antiviral responses.Like the toll-like receptor 3 (TLR3), the melanoma differentiation-associated protein 5 (MDA5) recognizes double-stranded (ds) RNA, a molecular pattern associated with viral infection.MDA5, a member of the DEAD/DEAH-box RNA helicase family, consists of an amino-terminal caspase recruitment domain (CARD) and a carboxyl-terminal RNA helicase domain similar to that of the related protein RIG-1.When stimulated by dsRNA, MDA5 recruits the adaptor protein VISA and ultimately causes the activation of IRF-3 and NF-kappaB.MDA5 and RIG-1 recognize different types of dsRNA, with MDA5 recognizing poly (I:C).MDA5-null mice were highly susceptible to infection with picornaviruses, which possess such sequences, demonstrating the importance of MDA5 in innate immunity.
    Synonyms: Melanoma differentiation-associated protein 5, Interferon-induced with helicase C domain protein 1, IFIH1
    NCBI登录号
    NP_071451
    途径
    Activation of Innate immune Response
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