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SYPL2 抗体 (C-Term)

SYPL2 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1887064
发货至: 中国
  • 抗原 See all SYPL2 抗体
    SYPL2 (Synaptophysin-Like 2 (SYPL2))
    抗原表位
    C-Term
    适用
    人, 小鼠, 大鼠
    宿主
    • 2
    克隆类型
    • 2
    多克隆
    标记
    • 2
    This SYPL2 antibody is un-conjugated
    应用范围
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
    交叉反应 (详细)
    At least two isoforms of SYPL2 are known to exist. SYPL2 antibody will not cross-react with SYPL1.
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    15 amino acid peptide near the carboxy terminus of human SYPL.
    Top Product
    Discover our top product SYPL2 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    注意事项
    Avoid freezing and thawing repeatly.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 4 °C for short term use.Store at -20 °C for long term preservation.
  • 抗原
    SYPL2 (Synaptophysin-Like 2 (SYPL2))
    别名
    SYPL2 (SYPL2 产品)
    别名
    AI552439 antibody, Mg29 antibody, MG29 antibody, mg29 antibody, MGC88982 antibody, Sypl antibody, fc22a07 antibody, wu:fc22a07 antibody, zgc:110355 antibody, sypl antibody, wu:fd54d09 antibody, zgc:65838 antibody, synaptophysin-like 2 antibody, synaptophysin like 2 antibody, synaptophysin like 2 S homeolog antibody, synaptophysin-like 2b antibody, synaptophysin-like 2a antibody, Sypl2 antibody, SYPL2 antibody, sypl2.S antibody, sypl2 antibody, sypl2b antibody, sypl2a antibody
    背景
    SYPL2, also known as Mitsugumin 29, was initially identified as a transmembrane protein from the triad junction in skeletal muscle that had significant homology with members of the synaptophysin family.SYPL2 is thought to participate in the excitation-contraction coupling process of skeletal muscle as SYPL2-null mice showed reduced muscle contractile force and altered triad junction structure and increased susceptibility to fatigue of the skeletal muscle.SYPL2 plays a critical role in muscle Ca2+ signaling by regulating the process of store-operated Ca2+ entry and interacts with ryanodine receptor (RyR), thereby influencing intracellular Ca2+ homeostasis through changes in the RyR/Ca2+ release function.Co-expression of SYPL2 and RyR in cultured cells leads to apoptotic cell death resulting from the depletion of Ca2+ from the intracellular stores.
    Synonyms: SYPL2, Synaptophysin-like protein 2, mitsugumin 29, MG29
    NCBI登录号
    NP_001035799
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