OTUD5 抗体 (C-Term)
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- 抗原 See all OTUD5 抗体
- OTUD5 (OTU Domain Containing 5 (OTUD5))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This OTUD5 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- 13 amino acid peptide near the carboxy terminus of the human OTUD5.
- Top Product
- Discover our top product OTUD5 Primary Antibody
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anti-OTU Domain Containing 5 (OTUD5) (AA 51-183) antibody
OTUD5 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-OTU Domain Containing 5 (OTUD5) (AA 550-600) antibodyOTUD5 适用: 人, 小鼠, 大鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-OTU Domain Containing 5 (OTUD5) (AA 501-571) antibodyOTUD5 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-OTU Domain Containing 5 (OTUD5) (C-Term) antibodyOTUD5 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
- 注意事项
- Avoid freezing and thawing repeatly.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 4 °C for short term use.Store at -20 °C for long term preservation.
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- 抗原
- OTUD5 (OTU Domain Containing 5 (OTUD5))
- 别名
- OTUD5 (OTUD5 产品)
- 别名
- DUBA antibody, AA407879 antibody, AI553596 antibody, BB114028 antibody, DXImx46e antibody, Sfc7 antibody, otud5 antibody, si:bz30i22.1 antibody, si:rp71-30i22.1 antibody, zgc:154072 antibody, wu:fi28a06 antibody, zgc:100839 antibody, OTU deubiquitinase 5 antibody, OTU domain containing 5 antibody, OTU deubiquitinase 5a antibody, OTU deubiquitinase 5 S homeolog antibody, OTU deubiquitinase 5 L homeolog antibody, OTU deubiquitinase 5b antibody, OTUD5 antibody, Otud5 antibody, otud5a antibody, otud5.S antibody, otud5.L antibody, otud5b antibody
- 背景
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OTUD5 is a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily.The OTU domain confers deubiquitinase activity and OTUD5 has been shown to suppress the type I interferon (IFN-I)-dependent innate immune response by cleaving the polyubiquitin chain from TRAF3, an essential type I interferon adaptor protein.Cleavage results in disassociation of TRAF3 from a downstream signaling complex containing TBK1 and the disruption of the IFN-I signaling cascade, indicating that OTUD5 acts as a negative regulator of innate immune responses.It has been suggested that by suppressing IFN-I production, OTUD5 may function to inhibit the emergence of certain autoimmune disorders such as systemic lupus erythematosus.Multiple isoforms of OTUD5 are known to exist.
Synonyms: OTU domain-containing protein 5, Deubiquitinating enzyme A, DUBA
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