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IKK alpha 抗体 (AA 658-674)

CHUK 适用: 人 WB, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1886894
发货至: 中国
  • 抗原 See all IKK alpha (CHUK) 抗体
    IKK alpha (CHUK) (conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK))
    抗原表位
    • 18
    • 15
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    AA 658-674
    适用
    • 131
    • 75
    • 53
    • 7
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    • 1
    宿主
    • 146
    • 12
    • 1
    克隆类型
    • 137
    • 22
    多克隆
    标记
    • 79
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    This IKK alpha antibody is un-conjugated
    应用范围
    • 125
    • 69
    • 36
    • 27
    • 26
    • 18
    • 16
    • 15
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    • 6
    • 5
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    Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
    交叉反应 (详细)
    This polyclonal antibody has no cross response to IKKb or IKKy.
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    Peptide corresponding to amino acids 658 to 674 of human IKK alpha, which differs from corresponding murine sequence by one amino acid.
    Top Product
    Discover our top product CHUK Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    注意事项
    Avoid freezing and thawing repeatly.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 4 °C for short term use.Store at -20 °C for long term preservation.
  • 抗原
    IKK alpha (CHUK) (conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK))
    别名
    IKK alpha (CHUK 产品)
    别名
    ikk antibody, ikk1 antibody, ikka antibody, ikkalpha antibody, CHUK antibody, IKBKA antibody, IKK-alpha antibody, IKK1 antibody, IKKA antibody, NFKBIKA antibody, TCF16 antibody, AI256658 antibody, Chuk1 antibody, Fbx24 antibody, Fbxo24 antibody, Ikka antibody, zgc:56539 antibody, conserved helix-loop-helix ubiquitous kinase S homeolog antibody, conserved helix-loop-helix ubiquitous kinase antibody, chuk.S antibody, CHUK antibody, Chuk antibody, chuk antibody
    背景
    Nuclear factor kappa B (NF-kappaB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses.NF-kappaB mediates the expression of a great variety of genes in response to extracellular stimuli including IL-1, TNFalpha and bacteria product LPS.NF-kappaB is associated with IkappaB proteins in the cell cytoplasm, which inhibit NF-kappaB activity.The long-sought IkappaB kinase (IKK), which phosphorylates IkappaB, and mediates IkappaB degradation and NF-kappaB activation, was recently identified by several laboratories.IKK is a serine protein kinase, and the IKK complex contains alpha and beta subunits (IKKalpha and IKKbeta).IKKalpha and IKKbeta interact with each other and both are essential for the NF-kappaB activation.IKKalpha specifically phosphorylates IkappaB-alpha.IKKalpha is expressed in a variety of human tissues.
    Synonyms: IKK-1, IKKa
    分子量
    87 kDa
    途径
    PI3K-Akt Signaling, NF-kappaB Signaling, RTK signaling, TCR Signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins
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