RHOA 抗体 (AA 101-150)
Our Local Distributor
北京 101111
Quick Overview for RHOA 抗体 (AA 101-150) (ABIN1886746)
抗原
See all RHOA 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 101-150
-
免疫原
- KLH conjugated synthetic peptide derived from human RhoA (101-150aa)
-
-
-
-
应用备注
-
Suggested dilutions:
Western blotting: 1.100-1.500 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- 0.01 M PBS, pH 7.4 with 10 mg/ml BSA and 0.1 % Sodium azide
-
储存液
- Sodium azide
-
注意事项
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
-
储存条件
- -20 °C
-
储存方法
- Store at -20 °C/1 year
-
有效期
- 12 months
-
-
- RHOA (Ras Homolog Gene Family, Member A (RHOA))
-
别名
- RhoA
-
背景
-
This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades.Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility.The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane.It is thought to be important in cell locomotion.Overexpression of this gene is associated with tumor cell proliferation and metastasis.Multiple alternatively spliced variants, encoding the same protein, have been identified.References: Graham D.L.et al.Chem.Biol.9:375-381(2002) Snyder J.T.et al.Nat.Struct.Biol.9:468-475(2002) Longenecker K.et al.Acta Crystallogr.D 59:876-880(2003)
Synonyms: RhoA protein, Aplysia ras related homolog 12, ARH 12, ARH12 -
分子量
- 21 kDa
-
UniProt
- P61586
-
途径
- Microtubule Dynamics, WNT signaling, Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Actin Filament Polymerization, Cell-Cell Junction Organization, Positive Regulation of Endopeptidase Activity, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, SARS-CoV-2 Protein Interactome
抗原
-