Renin in Preproprotein (AA 70-302) 抗体
适用: 人
IHC, WB
宿主: 兔
Polyclonal
unconjugated
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- 抗原
- Renin in Preproprotein
- 抗原表位
- AA 70-302
- 适用
- 人
- 宿主
- 兔
- 克隆类型
- 多克隆
- 应用范围
- Immunohistochemistry (IHC), Western Blotting (WB)
- 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 70 and 302 of Human REN
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- 应用备注
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250 - 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- Biohazard Informations: This product contains thimerosal which is hazardous.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- 抗原
- Renin in Preproprotein
- 背景
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Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure.Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance.Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined.Mutations in this gene have been shown to cause familial hyperproreninemia.[provided by RefSeq]
Synonyms: FLJ10761 - 分子量
- 45 kDa
- 基因ID
- 5972
- NCBI登录号
- NP_000528, NM_000537
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