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JNK 抗体 (AA 5-270)

This anti-JNK antibody is a 兔 多克隆 antibody detecting JNK in WB 和 IF. Suitable for 人.
产品编号 ABIN1886515
发货至: 中国

Quick Overview for JNK 抗体 (AA 5-270) (ABIN1886515)

抗原

See all JNK (MAPK8) 抗体
JNK (MAPK8) (Mitogen-Activated Protein Kinase 8 (MAPK8))

适用

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宿主

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克隆类型

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多克隆

标记

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This JNK antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

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    AA 5-270

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein fragment contain a sequence corresponding to a region within amino acids 5 and 270 of JNK1
  • 应用备注

    Suggested dilutions:
    Western blotting: 1.500-1.3000
    Immunofluorescence: 1.100-1.200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

    储存液

    Thimerosal (Merthiolate)

    注意事项

    Biohazard Informations: This product contains thimerosal which is hazardous.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • 抗原

    JNK (MAPK8) (Mitogen-Activated Protein Kinase 8 (MAPK8))

    别名

    JNK1

    背景

    The protein encoded by this gene is a member of the MAP kinase family.MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development.This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli.The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis.This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway.Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation.Four alternatively spliced transcript variants encoding distinct isoforms have been reported.[provided by RefSeq]

    分子量

    48 kDa

    基因ID

    5599

    NCBI登录号

    NM_139049, NP_620637

    途径

    MAPK Pathway, WNT signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, S100 Proteins
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