PRKACA 抗体 (AA 1-340)
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北京 101111
Quick Overview for PRKACA 抗体 (AA 1-340) (ABIN1885909)
抗原
See all PRKACA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-340
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 340 of PRKACA
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应用备注
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200 -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- Biohazard Informations: This product contains thimerosal which is hazardous.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- PRKACA (Protein Kinase A, alpha (PRKACA))
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别名
- PRKACA
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背景
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CAMP is a signaling molecule important for a variety of cellular functions.cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins.The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits.cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits.Four different regulatory subunits and three catalytic subunits have been identified in humans.The protein encoded by this gene is a member of the Ser/Thr protein kinase family and is a catalytic subunit of cAMP-dependent protein kinase.Alternatively spliced transcript variants encoding distinct isoforms have been observed.[provided by RefSeq]
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分子量
- 41 kDa
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基因ID
- 5566
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途径
- NF-kappaB Signaling, Hedgehog Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Carbohydrate Homeostasis, Myometrial Relaxation and Contraction, M Phase, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, Lipid Metabolism, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
抗原
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