APEX1 抗体 (AA 1-15)
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北京 101111
Quick Overview for APEX1 抗体 (AA 1-15) (ABIN1885631)
抗原
See all APEX1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-15
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纯化方法
- Affinity purified by Protein A.
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免疫原
- Synthetic peptide contain a sequence corresponding to a region within amino acids 1 and 15 of APE1
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应用备注
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200 -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- Biohazard Informations: This product contains thimerosal which is hazardous.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- APEX1 (Apurinic/Apyrimidinic Endonuclease 1 (APEX1))
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别名
- APE1
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背景
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Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases.AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites.Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site.This gene encodes the major AP endonuclease in human cells.Splice variants have been found for this gene, all encode the same protein.[provided by RefSeq]
Synonyms: APE, APE-1, APE1, APEN, APEX, APX, HAP1, REF-1, REF1 -
分子量
- 36 kDa
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基因ID
- 328
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NCBI登录号
- NP_001632, NM_001641
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途径
- DNA Damage Repair, Chromatin Binding, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Positive Regulation of Response to DNA Damage Stimulus
抗原
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