PCNA 抗体 (C-Term)
Quick Overview for PCNA 抗体 (C-Term) (ABIN1882273)
抗原
See all PCNA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 236-261, C-Term
-
预测反应
- B, Ha, Pr
-
纯化方法
- This antibody is purified through a protein G column, followed by dialysis against PBS.
-
免疫原
- This PCNA antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 236-261 amino acids from the C-terminal region of human PCNA.
-
亚型
- IgG1
-
-
-
-
应用备注
- WB: 1:2000. IHC: 1:2000. IHC-P: 1:25. IHC-P: 1:25
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
有效期
- 6 months
-
-
-
: "The DNA sequence and comparative analysis of human chromosome 20. ..." in: Nature, Vol. 414, Issue 6866, pp. 865-71, (2002) (PubMed).
-
: "The DNA sequence and comparative analysis of human chromosome 20. ..." in: Nature, Vol. 414, Issue 6866, pp. 865-71, (2002) (PubMed).
-
- PCNA (Proliferating Cell Nuclear Antigen (PCNA))
-
别名
- PCNA
-
背景
- This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2.
-
分子量
- 28769
-
NCBI登录号
- NP_002583, NP_872590
-
UniProt
- P12004
-
途径
- Telomere Maintenance, DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Autophagy
抗原
-