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ZBTB7B 抗体 (C-Term)

ZBTB7B 适用: 人 WB, IF 宿主: 兔 Polyclonal RB13260 unconjugated
产品编号 ABIN1882155
发货至: 中国
  • 抗原 See all ZBTB7B 抗体
    ZBTB7B (Zinc Finger and BTB Domain Containing 7B (ZBTB7B))
    抗原表位
    • 7
    • 7
    • 6
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 440-469, C-Term
    适用
    • 34
    • 12
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 29
    • 5
    克隆类型
    • 31
    • 3
    多克隆
    标记
    • 19
    • 3
    • 3
    • 3
    • 3
    • 3
    This ZBTB7B antibody is un-conjugated
    应用范围
    • 34
    • 22
    • 9
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This ZBTB7B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 440-469 amino acids from the C-terminal region of human ZBTB7B.
    克隆位点
    RB13260
    亚型
    Ig Fraction
    Top Product
    Discover our top product ZBTB7B Primary Antibody
  • 应用备注
    IF: 1:10~50. WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Matsumoto, Nagoshi, Yoshida, Kato, Kuroda, Shimura, Kaneko, Horiike, Nakamura, Taniwaki: "Expression of Master Regulators of T-cell, Helper T-cell and Follicular Helper T-cell Differentiation in Angioimmunoblastic T-cell Lymphoma." in: Internal medicine (Tokyo, Japan), Vol. 56, Issue 21, pp. 2851-2856, (2018) (PubMed).

    Matsumoto, Horiike, Ohshiro, Yamamoto, Sasaki, Tsutsumi, Kobayashi, Shimizu, Uchiyama, Kuroda, Nomura, Shimazaki, Taniwaki: "Expression of master regulators of helper T-cell differentiation in peripheral T-cell lymphoma, not otherwise specified, by immunohistochemical analysis." in: American journal of clinical pathology, Vol. 133, Issue 2, pp. 281-90, (2010) (PubMed).

    Galéra, Musso, Ducy, Karsenty: "c-Krox, a transcriptional regulator of type I collagen gene expression, is preferentially expressed in skin." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, Issue 20, pp. 9372-6, (1994) (PubMed).

  • 抗原
    ZBTB7B (Zinc Finger and BTB Domain Containing 7B (ZBTB7B))
    别名
    ZBTB7B (ZBTB7B 产品)
    别名
    THPOK antibody, ZBTB15 antibody, ZFP-67 antibody, ZFP67 antibody, ZNF857B antibody, c-KROX antibody, hcKROX antibody, Thpok antibody, Zfp67 antibody, c-Krox antibody, ZBTB7B antibody, zbtb7b antibody, MGC130914 antibody, zinc finger and BTB domain containing 7B antibody, kruppel-related zinc finger protein hcKrox antibody, ZBTB7B antibody, Zbtb7b antibody, zbtb7b antibody
    背景
    ZBTB7B is a transcription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors. It is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. ZBTB7B is a transcriptional repressor of the collagen COL1A1 and COL1A2 genes. It may also function as a repressor of fibronectin and possibly other extracellular matrix genes.
    分子量
    58027
    NCBI登录号
    NP_001239335, NP_001243384
    UniProt
    O15156
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