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RENT1/UPF1 抗体 (N-Term)

Name: RENT1/UPF1 抗体 (N-Term)
SKU: ABIN1882125
Availability: OutOfStock

UPF1 适用: 人 WB 宿主: 兔 Polyclonal RB8018 unconjugated

All lanes : Anti-RENT1 Antibody (N-term E22) at 1:1000 dilution Lane 1: HepG2 whole cell lysate Lane 2: SH-SY5Y whole cell lysate Lysates/proteins at 20 μg per lane. (RENT1/UPF1 抗体 (N-Term))

1 image

(5 references)

产品编号 ABIN1882125

发货至: 中国

Datasheet as PDF

抗原 See all RENT1/UPF1 (UPF1) 抗体

RENT1/UPF1 (UPF1) (UPF1 Regulator of Nonsense Transcripts Homolog (UPF1))
抗原表位
15

5

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 7-37, N-Term
适用
48

15

6

3

2

2

2

1

1

1

1

1
人
宿主
42

3

3
兔
Compatible Secondaries
克隆类型
40

8
多克隆
标记
30

3

2

2

1

1

1

1

1

1

1

1

1

1

1
This RENT1/UPF1 antibody is un-conjugated
应用范围
26

18

14

14

9

8

7

7

3

2

1

1

1
Western Blotting (WB)

预测反应

M

纯化方法

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

免疫原

This RENT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-37 amino acids from the N-terminal region of human RENT1.

克隆位点

RB8018

亚型

Ig Fraction

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UPF1 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-UPF1 Regulator of Nonsense Transcripts Homolog (UPF1) antibody
UPF1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-UPF1 Regulator of Nonsense Transcripts Homolog (UPF1) antibody
UPF1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-UPF1 Regulator of Nonsense Transcripts Homolog (UPF1) antibody
UPF1 适用: 人 WB, IF, IP 宿主: 兔 Monoclonal unconjugated

anti-UPF1 Regulator of Nonsense Transcripts Homolog (UPF1) (AA 578-614), (Middle Region) antibody
UPF1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-UPF1 Regulator of Nonsense Transcripts Homolog (UPF1) (AA 301-450) antibody
UPF1 适用: 人 ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-UPF1 Regulator of Nonsense Transcripts Homolog (UPF1) (AA 583-612) antibody
UPF1 适用: 人 WB 宿主: 兔 Polyclonal RB8354 unconjugated

anti-UPF1 Regulator of Nonsense Transcripts Homolog (UPF1) (AA 1019-1116) antibody
UPF1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4G3 unconjugated

anti-UPF1 Regulator of Nonsense Transcripts Homolog (UPF1) (AA 7-37) antibody
UPF1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-UPF1 Regulator of Nonsense Transcripts Homolog (UPF1) (AA 956-1125) antibody
UPF1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:1000

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

有效期

6 months
Kang, Shen, Macdonald: "Two molecular pathways (NMD and ERAD) contribute to a genetic epilepsy associated with the GABA(A) receptor GABRA1 PTC mutation, 975delC, S326fs328X." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 29, Issue 9, pp. 2833-44, (2009) (PubMed).

Ohnishi, Yamashita, Kashima, Schell, Anders, Grimson, Hachiya, Hentze, Anderson, Ohno: "Phosphorylation of hUPF1 induces formation of mRNA surveillance complexes containing hSMG-5 and hSMG-7." in: Molecular cell, Vol. 12, Issue 5, pp. 1187-200, (2003) (PubMed).

Mendell, ap Rhys, Dietz: "Separable roles for rent1/hUpf1 in altered splicing and decay of nonsense transcripts." in: Science (New York, N.Y.), Vol. 298, Issue 5592, pp. 419-22, (2002) (PubMed).

Lykke-Andersen: "Identification of a human decapping complex associated with hUpf proteins in nonsense-mediated decay." in: Molecular and cellular biology, Vol. 22, Issue 23, pp. 8114-21, (2002) (PubMed).

Carastro, Tan, Selg, Jack, So, Downey: "Identification of delta helicase as the bovine homolog of HUPF1: demonstration of an interaction with the third subunit of DNA polymerase delta." in: Nucleic acids research, Vol. 30, Issue 10, pp. 2232-43, (2002) (PubMed).
抗原

RENT1/UPF1 (UPF1) (UPF1 Regulator of Nonsense Transcripts Homolog (UPF1))

别名

RENT1 (UPF1 产品)

别名

HUPF1 antibody, NORF1 antibody, RENT1 antibody, pNORF1 antibody, smg-2 antibody, B430202H16Rik antibody, PNORF-1 antibody, Rent1 antibody, Upflp antibody, rent1 antibody, wu:fi40f07 antibody, wu:fj48a01 antibody, zgc:55472 antibody, Tb05.3C6.50 antibody, AO090012000584 antibody, hupf1 antibody, norf1 antibody, pnorf1 antibody, upf1 antibody, UPF1, RNA helicase and ATPase antibody, UPF1 regulator of nonsense transcripts homolog (yeast) antibody, upf1 regulator of nonsense transcripts homolog (yeast) antibody, regulator of nonsense transcripts 1 antibody, Regulator of nonsense transcripts 1 antibody, UPF1 regulator of nonsense transcripts homolog S homeolog antibody, UPF1 antibody, Upf1 antibody, upf1 antibody, Tc00.1047053511317.30 antibody, Tb927.5.2140 antibody, TVAG_453890 antibody, TVAG_237840 antibody, AOR_1_1018194 antibody, HPB8_739 antibody, smg-2 antibody, upf1.S antibody

背景

RENT1 is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping.

分子量

124345

NCBI登录号

NP_002902

UniProt

Q92900

途径

SARS-CoV-2 Protein Interactome