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Neuregulin 2 抗体 (C-Term)

Name: Neuregulin 2 抗体 (C-Term)
SKU: ABIN1882105
Availability: OutOfStock

This anti-Neuregulin 2 antibody is a 兔多克隆 antibody detecting Neuregulin 2 in WB 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 5+ publications.

Anti-NRG2 Antibody at 1:1000 dilution + HT-29 whole cell lysate Lysates/proteins at 20 μg per lane. (Neuregulin 2 抗体 (C-Term))

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. (Neuregulin 2 抗体 (C-Term))

IHC (p)

2 images

(5 references)

产品编号 ABIN1882105

发货至: 中国

Quick Overview for Neuregulin 2 抗体 (C-Term) (ABIN1882105)

抗原

See all Neuregulin 2 (NRG2) 抗体

Neuregulin 2 (NRG2)

适用

人

宿主

兔

克隆类型

多克隆

标记

This Neuregulin 2 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB1278

Discover our top product NRG2 Primary Antibody

抗原表位
7

6

3

2

2

1

1

1

1

1

1

1

1
AA 358-389, C-Term

预测反应

Rat

纯化方法

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

免疫原

This NRG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 358-389 amino acids from the C-terminal region of human NRG2.

亚型

Ig Fraction
anti-Neuregulin 2 (NRG2) antibody
NRG2 适用: 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Neuregulin 2 (NRG2) (AA 116-215) antibody
NRG2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3D2 unconjugated

anti-Neuregulin 2 (NRG2) (AA 112-405) antibody
NRG2 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Neuregulin 2 (NRG2) antibody
NRG2 适用: 人, 大鼠, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Neuregulin 2 (NRG2) (Internal Region) antibody
NRG2 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Neuregulin 2 (NRG2) (AA 116-215) antibody
NRG2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated

anti-Neuregulin 2 (NRG2) (AA 101-211) antibody
NRG2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Neuregulin 2 (NRG2) (AA 618-836) antibody
NRG2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Neuregulin 2 (NRG2) (AA 830-855) antibody
NRG2 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Neuregulin 2 (NRG2) (AA 297-311), (Extracellular) antibody
NRG2 适用: 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:1000. IHC-P: 1:50~100

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

有效期

6 months
Yamada, Ichino, Nishii, Sawada, Higashiyama, Ishiguro, Nagatsu: "Characterization of the human NTAK gene structure and distribution of the isoforms for rat NTAK mRNA." in: Gene, Vol. 255, Issue 1, pp. 15-24, (2000) (PubMed).

Ring, Chang, Guilbot, Brice, LeGuern, Francke: "The human neuregulin-2 (NRG2) gene: cloning, mapping and evaluation as a candidate for the autosomal recessive form of Charcot-Marie-Tooth disease linked to 5q." in: Human genetics, Vol. 104, Issue 4, pp. 326-32, (1999) (PubMed).

Higashiyama, Horikawa, Yamada, Ichino, Nakano, Nakagawa, Miyagawa, Matsushita, Nagatsu, Taniguchi, Ishiguro: "A novel brain-derived member of the epidermal growth factor family that interacts with ErbB3 and ErbB4." in: Journal of biochemistry, Vol. 122, Issue 3, pp. 675-80, (1998) (PubMed).

Carraway, Weber, Unger, Ledesma, Yu, Gassmann, Lai: "Neuregulin-2, a new ligand of ErbB3/ErbB4-receptor tyrosine kinases." in: Nature, Vol. 387, Issue 6632, pp. 512-6, (1997) (PubMed).

Busfield, Michnick, Chickering, Revett, Ma, Woolf, Comrack, Dussault, Woolf, Goodearl, Gearing: "Characterization of a neuregulin-related gene, Don-1, that is highly expressed in restricted regions of the cerebellum and hippocampus." in: Molecular and cellular biology, Vol. 17, Issue 7, pp. 4007-14, (1997) (PubMed).
抗原

Neuregulin 2 (NRG2)

别名

NRG2

背景

Neuregulin 2 (NRG2) is a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the Erbb family of receptors, NRG2 induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The gene consists of 12 exons and the genomic structure is similar to that of neuregulin 1 (NRG1), another member of the neuregulin family of ligands. NRG1 and NRG2 mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells. There are six NRG2 alternatively spliced transcripts which are variable between the epidermal growth factor-like (EGF-like) and the transmembrane domains. The gene is located close to the region for demyelinating Charcot-Marie-Tooth disease locus, but is not responsible for this disease.

分子量

91679

NCBI登录号

NP_001171864, NP_004874, NP_053584, NP_053585, NP_053586

UniProt

O14511

途径

RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway