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USH1C 抗体 (N-Term)

USH1C 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB41722 unconjugated
产品编号 ABIN1881984
发货至: 中国
  • 抗原 See all USH1C 抗体
    USH1C (Usher Syndrome 1C (Autosomal Recessive, Severe) (USH1C))
    抗原表位
    • 13
    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    AA 1-30, N-Term
    适用
    • 28
    • 10
    • 3
    • 1
    人, 小鼠
    宿主
    • 24
    • 4
    • 1
    克隆类型
    • 26
    • 3
    多克隆
    标记
    • 15
    • 4
    • 3
    • 3
    • 2
    • 2
    This USH1C antibody is un-conjugated
    应用范围
    • 22
    • 22
    • 5
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    预测反应
    B
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This USH1C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human USH1C.
    克隆位点
    RB41722
    亚型
    Ig Fraction
    Top Product
    Discover our top product USH1C Primary Antibody
  • 应用备注
    WB: 1:1000. WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Yan, Pan, Chen, Wu, Zhang: "The structure of the harmonin/sans complex reveals an unexpected interaction mode of the two Usher syndrome proteins." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 9, pp. 4040-5, (2010) (PubMed).

    Jaijo, Aller, García-García, Aparisi, Bernal, Avila-Fernández, Barragán, Baiget, Ayuso, Antiñolo, Díaz-Llopis, Külm, Beneyto, Nájera, Millán: "Microarray-based mutation analysis of 183 Spanish families with Usher syndrome." in: Investigative ophthalmology & visual science, Vol. 51, Issue 3, pp. 1311-7, (2010) (PubMed).

    Pan, Yan, Wu, Zhang: "Assembling stable hair cell tip link complex via multidentate interactions between harmonin and cadherin 23." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 14, pp. 5575-80, (2009) (PubMed).

    Hanna, Kruskal, Ezekowitz, Bloom, Collier: "Role of macrophage oxidative burst in the action of anthrax lethal toxin." in: Molecular medicine (Cambridge, Mass.), Vol. 1, Issue 1, pp. 7-18, (1996) (PubMed).

  • 抗原
    USH1C (Usher Syndrome 1C (Autosomal Recessive, Severe) (USH1C))
    别名
    USH1C (USH1C 产品)
    别名
    AIE-75 antibody, DFNB18 antibody, DFNB18A antibody, NY-CO-37 antibody, NY-CO-38 antibody, PDZ-45 antibody, PDZ-73 antibody, PDZ-73/NY-CO-38 antibody, PDZ73 antibody, PDZD7C antibody, ush1cpst antibody, 2010016F01Rik antibody, harmonin antibody, zgc:136806 antibody, ush1c antibody, USH1 protein network component harmonin antibody, harmonin antibody, Usher syndrome 1C antibody, USH1 protein network component harmonin L homeolog antibody, USH1C antibody, CpipJ_CPIJ012732 antibody, Ush1c antibody, ush1c antibody, ush1c.L antibody
    背景
    This gene encodes a scaffold protein that functions in the assembly of Usher protein complexes. The protein contains PDZ domains, a coiled-coil region with a bipartite nuclear localization signal and a PEST degradation sequence. Defects in this gene are the cause of Usher syndrome type 1C and non-syndromic sensorineural deafness autosomal recessive type 18. Multiple transcript variants encoding different isoforms have been found for this gene.
    分子量
    62211
    NCBI登录号
    NP_005700, NP_710142
    UniProt
    Q9Y6N9
    途径
    Sensory Perception of Sound
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