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UGT2B4 抗体 (N-Term)

UGT2B4 适用: 人 WB 宿主: 兔 Polyclonal RB41766 unconjugated
产品编号 ABIN1881977
发货至: 中国
  • 抗原 See all UGT2B4 抗体
    UGT2B4 (UDP Glucuronosyltransferase 2 Family, Polypeptide B4 (UGT2B4))
    抗原表位
    • 15
    • 13
    • 7
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 68-96, N-Term
    适用
    • 43
    • 2
    • 2
    宿主
    • 42
    • 1
    克隆类型
    • 42
    • 1
    多克隆
    标记
    • 15
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This UGT2B4 antibody is un-conjugated
    应用范围
    • 37
    • 23
    • 13
    • 13
    • 6
    • 3
    • 3
    • 3
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This UGT2B4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 68-96 amino acids from the N-terminal region of human UGT2B4.
    克隆位点
    RB41766
    亚型
    Ig Fraction
    Top Product
    Discover our top product UGT2B4 Primary Antibody
  • 应用备注
    WB: 1:1000. WB: 1:8000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Lévesque, Ménard, Laverdière, Bellemare, Barbier, Girard, Guillemette: "Extensive splicing of transcripts encoding the bile acid-conjugating enzyme UGT2B4 modulates glucuronidation." in: Pharmacogenetics and genomics, Vol. 20, Issue 3, pp. 195-210, (2010) (PubMed).

    Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).

    Yong, Schwartz, Atkinson, Makar, Thomas, Newton, Aiello Bowles, Holt, Leisenring, Lampe: "Associations between polymorphisms in glucuronidation and sulfation enzymes and mammographic breast density in premenopausal women in the United States." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 19, Issue 2, pp. 537-46, (2010) (PubMed).

  • 抗原
    UGT2B4 (UDP Glucuronosyltransferase 2 Family, Polypeptide B4 (UGT2B4))
    别名
    UGT2B4 (UGT2B4 产品)
    别名
    HLUG25 antibody, UDPGTH1 antibody, UGT2B11 antibody, UDPGT2B4 antibody, UGT2B17 antibody, UGT2B28 antibody, UDP glucuronosyltransferase family 2 member B4 antibody, UDP-glucuronosyltransferase 2B4 antibody, UGT2B4 antibody, LOC615303 antibody, LOC100066359 antibody
    背景
    UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme is active on polyhydroxylated estrogens (such as estriol, 4-hydroxyestrone and 2-hydroxyestriol) and xenobiotics (such as 4-methylumbelliferone, 1-naphthol, 4-nitrophenol, 2-aminophenol, 4-hydroxybiphenyl and menthol). It is capable of 6 alpha-hydroxyglucuronidation of hyodeoxycholic acid.
    分子量
    60513
    NCBI登录号
    NP_066962
    UniProt
    P06133
    途径
    Steroid Hormone Biosynthesis
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