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Tuberin 抗体 (pThr1373)

Cited in 3+ publications. This anti-Tuberin antibody is a 兔 多克隆 antibody detecting Tuberin in DB. Suitable for 大鼠.
产品编号 ABIN1881935
发货至: 中国
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Quick Overview for Tuberin 抗体 (pThr1373) (ABIN1881935)

抗原

See all Tuberin (TSC2) 抗体
Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))

适用

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大鼠

宿主

  • 385
  • 14

克隆类型

  • 353
  • 46
多克隆

标记

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This Tuberin antibody is un-conjugated

应用范围

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Dot Blot (DB)

克隆位点

RB41276
  • 抗原表位

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    pThr1373

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This rat TSC2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T1373 of rat TSC2.

    亚型

    Ig Fraction
  • 应用备注

    DB: 1:500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Larson, Liu, Stevens, Li, Li, Evers, Gao: "Tuberous sclerosis complex 2 (TSC2) regulates cell migration and polarity through activation of CDC42 and RAC1." in: The Journal of biological chemistry, Vol. 285, Issue 32, pp. 24987-98, (2010) (PubMed).

    Di Nardo, Kramvis, Cho, Sadowski, Meikle, Kwiatkowski, Sahin: "Tuberous sclerosis complex activity is required to control neuronal stress responses in an mTOR-dependent manner." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 29, Issue 18, pp. 5926-37, (2009) (PubMed).

    Shiono, Kobayashi, Takahashi, Sun, Abe, Zhang, Wang, Piao, Takagi, Mineki, Taka, Tada, Sonobe, Momose, Ueda, Hino: "The G1556S-type tuberin variant suppresses tumor formation in tuberous sclerosis 2 mutant (Eker) rats despite its deficiency in mTOR inhibition." in: Oncogene, Vol. 27, Issue 52, pp. 6690-7, (2008) (PubMed).

  • 抗原

    Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))

    别名

    TSC2

    背景

    Acts as a tumor suppressor, may play a role in cell cycle regulation, acute phase response, and negative regulation of cell proliferation [RGD].

    分子量

    201278

    NCBI登录号

    NP_036812

    UniProt

    P49816

    途径

    RTK signaling, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus
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