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- 抗原 See all TAF11 抗体
- TAF11 (TATA Box Binding Protein Associated Factor 11 (TAF11))
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抗原表位
- AA 1-30, N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TAF11 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This TAF11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human TAF11.
- 克隆位点
- RB41941
- 亚型
- Ig Fraction
- Top Product
- Discover our top product TAF11 Primary Antibody
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- 应用备注
- WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage." in: Science (New York, N.Y.), Vol. 316, Issue 5828, pp. 1160-6, (2007) (PubMed).
: "The DNA sequence and analysis of human chromosome 6. ..." in: Nature, Vol. 425, Issue 6960, pp. 805-11, (2003) (PubMed).
: "The TBN protein, which is essential for early embryonic mouse development, is an inducible TAFII implicated in adipogenesis." in: Molecular cell, Vol. 12, Issue 4, pp. 991-1001, (2003) (PubMed).
: "The human transcription factor IID subunit human TATA-binding protein-associated factor 28 interacts in a ligand-reversible manner with the vitamin D(3) and thyroid hormone receptors." in: The Journal of biological chemistry, Vol. 275, Issue 14, pp. 10064-71, (2000) (PubMed).
: "Human TAF(II)28 and TAF(II)18 interact through a histone fold encoded by atypical evolutionary conserved motifs also found in the SPT3 family." in: Cell, Vol. 94, Issue 2, pp. 239-49, (1998) (PubMed).
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ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage." in: Science (New York, N.Y.), Vol. 316, Issue 5828, pp. 1160-6, (2007) (PubMed).
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- 抗原
- TAF11 (TATA Box Binding Protein Associated Factor 11 (TAF11))
- 别名
- TAF11 (TAF11 产品)
- 别名
- 1110038O14Rik antibody, 28kDa antibody, AI115401 antibody, AL024207 antibody, AW552398 antibody, PRO214 antibody, TAF2I antibody, TAFII28 antibody, MGC:15243 antibody, TATA-box binding protein associated factor 11 antibody, Taf11 antibody, TAF11 antibody
- 背景
- Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a small subunit of TFIID that is present in all TFIID complexes and interacts with TBP. This subunit also interacts with another small subunit, TAF13, to form a heterodimer with a structure similar to the histone core structure.
- 分子量
- 23307
- NCBI登录号
- NP_001257417, NP_005634
- UniProt
- Q15544
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