SMARCD1 抗体 (AA 309-335)
(6 references)-
- 抗原 See all SMARCD1 抗体
- SMARCD1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily D, Member 1 (SMARCD1))
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抗原表位
- AA 309-335
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SMARCD1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 预测反应
- B, H
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This Mouse Smarcd1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 309-335 amino acids from the Central region of mouse Smarcd1.
- 克隆位点
- RB40713
- 亚型
- Ig Fraction
- Top Product
- Discover our top product SMARCD1 Primary Antibody
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anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily D, Member 1 (SMARCD1) (AA 7-124) antibody
SMARCD1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily D, Member 1 (SMARCD1) (AA 1-120) antibodySMARCD1 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily D, Member 1 (SMARCD1) antibodySMARCD1 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily D, Member 1 (SMARCD1) (AA 180-229) antibodySMARCD1 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠, 非洲爪蟾, 小鸡, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily D, Member 1 (SMARCD1) (AA 216-515) antibodySMARCD1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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: "SWI/SNF factors required for cellular resistance to DNA damage include ARID1A and ARID1B and show interdependent protein stability." in: Cancer research, Vol. 74, Issue 9, pp. 2465-75, (2014) (PubMed).
: "Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst." in: Developmental cell, Vol. 18, Issue 4, pp. 675-85, (2010) (PubMed).
: "An embryonic stem cell chromatin remodeling complex, esBAF, is essential for embryonic stem cell self-renewal and pluripotency." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 13, pp. 5181-6, (2009) (PubMed).
: "Genome-wide coactivation analysis of PGC-1alpha identifies BAF60a as a regulator of hepatic lipid metabolism." in: Cell metabolism, Vol. 8, Issue 2, pp. 105-17, (2008) (PubMed).
: "BAF60a interacts with p53 to recruit the SWI/SNF complex." in: The Journal of biological chemistry, Vol. 283, Issue 18, pp. 11924-34, (2008) (PubMed).
: "Transcriptional profiling of Wnt4 mutant mouse kidneys identifies genes expressed during nephron formation." in: Gene expression patterns : GEP, Vol. 8, Issue 5, pp. 297-306, (2008) (PubMed).
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: "SWI/SNF factors required for cellular resistance to DNA damage include ARID1A and ARID1B and show interdependent protein stability." in: Cancer research, Vol. 74, Issue 9, pp. 2465-75, (2014) (PubMed).
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- 抗原
- SMARCD1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily D, Member 1 (SMARCD1))
- 别名
- Smarcd1 (SMARCD1 产品)
- 别名
- rsc6p antibody, baf60a antibody, cracd1 antibody, MGC69403 antibody, BAF60A antibody, CRACD1 antibody, Rsc6p antibody, wu:fa10h07 antibody, wu:fb82d01 antibody, wu:fi45f10 antibody, AA407987 antibody, Baf60a antibody, D15Kz1 antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 L homeolog antibody, SMARCD1 antibody, smarcd1 antibody, smarcd1.L antibody, Smarcd1 antibody
- 背景
- Smarcd1 is involved in chromatin remodeling. Has a strong influence on the Vitamin D-mediated transcriptional activity from an enhancer Vitamin D receptor element (VDRE). May be a link between mammalian SWI-SNF-like chromatin remodeling complexes and the vitamin D receptor (VDR) heterodimer. Mediates critical interactions between nuclear receptors and the BRG1/SMARCA4 chromatin-remodeling complex for transactivation. Also involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene (By similarity). Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth.
- 分子量
- 58245
- NCBI登录号
- NP_114030
- UniProt
- Q61466
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