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SEMA7A 抗体 (N-Term)

SEMA7A 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1881787
发货至: 中国
  • 抗原 See all SEMA7A 抗体
    SEMA7A (Semaphorin 7A, GPI Membrane Anchor (John Milton Hagen Blood Group) (SEMA7A))
    抗原表位
    • 15
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 178-202, N-Term
    适用
    • 45
    • 31
    • 24
    • 6
    • 5
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 34
    • 12
    • 2
    克隆类型
    • 34
    • 14
    多克隆
    标记
    • 27
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SEMA7A antibody is un-conjugated
    应用范围
    • 42
    • 16
    • 13
    • 13
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This SEMA7A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 178-202 amino acids from the N-terminal region of human SEMA7A.
    亚型
    Ig Fraction
    Top Product
    Discover our top product SEMA7A Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Esnault, Torr, Bernau, Johansson, Kelly, Sandbo, Jarjour: "Endogenous Semaphorin-7A Impedes Human Lung Fibroblast Differentiation." in: PLoS ONE, Vol. 12, Issue 1, pp. e0170207, (2017) (PubMed).

    Seltsam, Strigens, Levene, Yahalom, Moulds, Moulds, Hustinx, Weisbach, Figueroa, Bade-Doeding, DeLuca, Blasczyk: "The molecular diversity of Sema7A, the semaphorin that carries the JMH blood group antigens." in: Transfusion, Vol. 47, Issue 1, pp. 133-46, (2007) (PubMed).

    Yamada, Kubo, Takeshita, Harashima, Kawano, Mine, Sagawa, Sugamura, Itoh: "Molecular cloning of a glycosylphosphatidylinositol-anchored molecule CDw108." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 162, Issue 7, pp. 4094-100, (1999) (PubMed).

    Angelisová, Drbal, Cerný, Hilgert, Horejsí: "Characterization of the human leukocyte GPI-anchored glycoprotein CDw108 and its relation to other similar molecules." in: Immunobiology, Vol. 200, Issue 2, pp. 234-45, (1999) (PubMed).

    Lange, Liehr, Goen, Gebhart, Fleckenstein, Ensser: "New eukaryotic semaphorins with close homology to semaphorins of DNA viruses." in: Genomics, Vol. 51, Issue 3, pp. 340-50, (1998) (PubMed).

  • 抗原
    SEMA7A (Semaphorin 7A, GPI Membrane Anchor (John Milton Hagen Blood Group) (SEMA7A))
    别名
    SEMA7A (SEMA7A 产品)
    别名
    2900057C09Rik antibody, CDw108 antibody, H-Sema-L antibody, M-Sema-L antibody, Semal antibody, CD108 antibody, H-SEMA-K1 antibody, JMH antibody, SEMAK1 antibody, SEMAL antibody, sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A antibody, semaphorin 7A (John Milton Hagen blood group) antibody, Sema7a antibody, SEMA7A antibody
    背景
    Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of proinflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T-cell-mediated immune responses. Promotes axon growth in the embryonic olfactory bulb. Promotes attachment, spreading and dendrite outgrowth in melanocytes.
    分子量
    74824
    NCBI登录号
    NP_001139501, NP_001139502, NP_003603
    UniProt
    O75326
    途径
    Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Cell Size
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