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PPP2R1A 抗体 (C-Term)

PPP2R1A 适用: 人 WB 宿主: 兔 Polyclonal RB41029 unconjugated
产品编号 ABIN1881682
发货至: 中国
  • 抗原 See all PPP2R1A 抗体
    PPP2R1A (Protein Phosphatase 2, Regulatory Subunit A, alpha (PPP2R1A))
    抗原表位
    • 15
    • 13
    • 12
    • 9
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 454-481, C-Term
    适用
    • 68
    • 40
    • 21
    • 12
    • 8
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    宿主
    • 65
    • 3
    • 2
    • 1
    克隆类型
    • 69
    • 2
    多克隆
    标记
    • 35
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PPP2R1A antibody is un-conjugated
    应用范围
    • 55
    • 21
    • 13
    • 13
    • 8
    • 8
    • 8
    • 7
    • 6
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    预测反应
    B, M, Pig
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This PPP2R1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 454-481 amino acids from the C-terminal region of human PPP2R1A.
    克隆位点
    RB41029
    亚型
    Ig Fraction
    Top Product
    Discover our top product PPP2R1A Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Jones, Wang, Shih, Mao, Nakayama, Roden, Glas, Slamon, Diaz, Vogelstein, Kinzler, Velculescu, Papadopoulos: "Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinoma." in: Science (New York, N.Y.), Vol. 330, Issue 6001, pp. 228-31, (2010) (PubMed).

    Schmitz, Held, Janssens, Hutchins, Hudecz, Ivanova, Goris, Trinkle-Mulcahy, Lamond, Poser, Hyman, Mechtler, Peters, Gerlich: "Live-cell imaging RNAi screen identifies PP2A-B55alpha and importin-beta1 as key mitotic exit regulators in human cells." in: Nature cell biology, Vol. 12, Issue 9, pp. 886-93, (2010) (PubMed).

    Dupont, Breyer, Bradley, Schuyler, Plummer, Sanders, Page, Smith: "Protein phosphatase 2A subunit gene haplotypes and proliferative breast disease modify breast cancer risk." in: Cancer, Vol. 116, Issue 1, pp. 8-19, (2010) (PubMed).

    Heikkinen, Nummela, Leivonen, Westermarck, Hill, Kähäri, Jaakkola: "Hypoxia-activated Smad3-specific dephosphorylation by PP2A." in: The Journal of biological chemistry, Vol. 285, Issue 6, pp. 3740-9, (2010) (PubMed).

    Wang, Gao, Wang, Flagg, Deng: "A nonhomologous end-joining pathway is required for protein phosphatase 2A promotion of DNA double-strand break repair." in: Neoplasia (New York, N.Y.), Vol. 11, Issue 10, pp. 1012-21, (2009) (PubMed).

  • 抗原
    PPP2R1A (Protein Phosphatase 2, Regulatory Subunit A, alpha (PPP2R1A))
    别名
    PPP2R1A (PPP2R1A 产品)
    别名
    PP2A-Aalpha antibody, PP2AAALPHA antibody, PR65A antibody, PR65 antibody, pp2a-aalpha antibody, pp2aaalpha antibody, ppp2r1a antibody, pr65a antibody, wu:fa02h04 antibody, zgc:56296 antibody, 6330556D22Rik antibody, PP2A antibody, ppp2r1a-a antibody, ppp2r1a-b antibody, protein phosphatase 2 scaffold subunit Aalpha antibody, protein phosphatase 2 scaffold subunit A alpha antibody, protein phosphatase 2 regulatory subunit A, alpha L homeolog antibody, protein phosphatase 2 regulatory subunit A, alpha antibody, protein phosphatase 2, regulatory subunit A, beta a antibody, serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform antibody, protein phosphatase 2, regulatory subunit A, alpha isoform antibody, protein phosphatase 2, regulatory subunit A, alpha antibody, protein phosphatase 2 regulatory subunit A, alpha S homeolog antibody, PPP2R1A antibody, Ppp2r1a antibody, ppp2r1a.L antibody, ppp2r1a antibody, ppp2r1ba antibody, LOC583227 antibody, ppp2r1a.S antibody
    背景
    This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes an alpha isoform of the constant regulatory subunit A. Alternatively spliced transcript variants have been described. [provided by RefSeq].
    分子量
    65309
    NCBI登录号
    NP_055040
    UniProt
    P30153
    途径
    PI3K-Akt Signaling, Mitotic G1-G1/S Phases, M Phase, Hepatitis C, Toll-Like Receptors Cascades
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