(4 references)-
- 抗原 See all PIGB 抗体
- PIGB (Phosphatidylinositol Glycan Anchor Biosynthesis, Class B (PIGB))
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抗原表位
- AA 28-56, N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PIGB antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This PIGB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-56 amino acids from the N-terminal region of human PIGB.
- 克隆位点
- RB32518
- 亚型
- Ig Fraction
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- 应用备注
- WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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: "siRNA-mediated inhibition of phosphatidylinositol glycan Class B (PIGB) confers resistance to methylmercury in HEK293 cells." in: The Journal of toxicological sciences, Vol. 32, Issue 5, pp. 581-3, (2008) (PubMed).
: "Evidence that Griscelli syndrome with neurological involvement is caused by mutations in RAB27A, not MYO5A." in: American journal of human genetics, Vol. 71, Issue 2, pp. 407-14, (2002) (PubMed).
: "Dissecting and manipulating the pathway for glycosylphos-phatidylinositol-anchor biosynthesis." in: Current opinion in chemical biology, Vol. 4, Issue 6, pp. 632-8, (2001) (PubMed).
: "PIG-B, a membrane protein of the endoplasmic reticulum with a large lumenal domain, is involved in transferring the third mannose of the GPI anchor." in: The EMBO journal, Vol. 15, Issue 16, pp. 4254-61, (1996) (PubMed).
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: "siRNA-mediated inhibition of phosphatidylinositol glycan Class B (PIGB) confers resistance to methylmercury in HEK293 cells." in: The Journal of toxicological sciences, Vol. 32, Issue 5, pp. 581-3, (2008) (PubMed).
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- 抗原
- PIGB (Phosphatidylinositol Glycan Anchor Biosynthesis, Class B (PIGB))
- 别名
- PIGB (PIGB 产品)
- 别名
- GPI-MT-III antibody, PIG-B antibody, Pig-b antibody, phosphatidylinositol glycan anchor biosynthesis, class B antibody, phosphatidylinositol glycan anchor biosynthesis class B antibody, phosphatidylinositol glycan anchor biosynthesis class B S homeolog antibody, Pigb antibody, PIGB antibody, pigb.S antibody
- 背景
- This gene encodes a transmembrane protein that is located in the endoplasmic reticulum and is involved in GPI-anchor biosynthesis. The glycosylphosphatidylinositol (GPI) anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This gene is thought to encode a member of a family of dolichol-phosphate-mannose (Dol-P-Man) dependent mannosyltransferases.
- 分子量
- 65056
- NCBI登录号
- NP_004846
- UniProt
- Q92521
- 途径
- Inositol Metabolic Process
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