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ERK1 抗体 (AA 182-211)

This anti-ERK1 antibody is a 兔 多克隆 antibody detecting ERK1 in WB. Suitable for 人. This Primary Antibody has been cited in 6+ publications.
产品编号 ABIN1881527
发货至: 中国

Quick Overview for ERK1 抗体 (AA 182-211) (ABIN1881527)

抗原

See all ERK1 (MAPK3) 抗体
ERK1 (MAPK3) (Mitogen-Activated Protein Kinase 3 (MAPK3))

适用

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宿主

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克隆类型

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多克隆

标记

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This ERK1 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB13301
  • 抗原表位

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    AA 182-211

    预测反应

    D, B, M, Rat, X, E

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This MAPK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 182-211 amino acids from human MAPK3.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Tetsunaga, Nishida, Furumatsu, Naruse, Hirohata, Yoshida, Saito, Ozaki: "Regulation of mechanical stress-induced MMP-13 and ADAMTS-5 expression by RUNX-2 transcriptional factor in SW1353 chondrocyte-like cells." in: Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society, Vol. 19, Issue 2, pp. 222-32, (2011) (PubMed).

    Munshi, Wu, Mukhopadhyay, Ottaviano, Sassano, Koblinski, Platanias, Stack et al.: "Differential regulation of membrane type 1-matrix metalloproteinase activity by ERK 1/2- and p38 MAPK-modulated tissue inhibitor of metalloproteinases 2 expression controls transforming growth ..." in: The Journal of biological chemistry, Vol. 279, Issue 37, pp. 39042-50, (2004) (PubMed).

    Mukherjee, Huang, Petkova, Albanese, Pestell, Braunstein, Christ, Wittner, Lisanti, Berman, Weiss, Tanowitz: "Trypanosoma cruzi infection activates extracellular signal-regulated kinase in cultured endothelial and smooth muscle cells." in: Infection and immunity, Vol. 72, Issue 9, pp. 5274-82, (2004) (PubMed).

    Sebkova, Pellicanò, Monteleone, Grazioli, Guarnieri, Imeneo, Pallone, Luzza: "Extracellular signal-regulated protein kinase mediates interleukin 17 (IL-17)-induced IL-8 secretion in Helicobacter pylori-infected human gastric epithelial cells." in: Infection and immunity, Vol. 72, Issue 9, pp. 5019-26, (2004) (PubMed).

    Huang, Chang, Liu: "Basic fibroblast growth factor antagonizes activin A-mediated growth inhibition and hemoglobin synthesis in K562 cells by activating ERK1/2 and deactivating p38 MAP kinase." in: Biochemical and biophysical research communications, Vol. 320, Issue 4, pp. 1247-52, (2004) (PubMed).

    Mizuno, Kadowaki, Demura, Ameshima, Miyamori, Ishizaki: "p42/44 Mitogen-activated protein kinase regulated by p53 and nitric oxide in human pulmonary arterial smooth muscle cells." in: American journal of respiratory cell and molecular biology, Vol. 31, Issue 2, pp. 184-92, (2004) (PubMed).

  • 抗原

    ERK1 (MAPK3) (Mitogen-Activated Protein Kinase 3 (MAPK3))

    别名

    MAPK3

    背景

    MAPK3 is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets.

    分子量

    43136

    NCBI登录号

    NP_001035145, NP_001103361, NP_002737

    UniProt

    P27361

    途径

    MAPK Pathway, RTK signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, S100 Proteins
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