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ERK1 抗体 (AA 182-211)

Name: ERK1 抗体 (AA 182-211)
SKU: ABIN1881527
Availability: OutOfStock

MAPK3 适用: 人 WB 宿主: 兔 Polyclonal RB13301 unconjugated

Western blot analysis of PK3 (arrow) using rabbit polyclonal PK3 Antibody (R). (ERK1 抗体 (AA 182-211))

1 image

(6 references)

产品编号 ABIN1881527

发货至: 中国

Datasheet as PDF

抗原 See all ERK1 (MAPK3) 抗体

ERK1 (MAPK3) (Mitogen-Activated Protein Kinase 3 (MAPK3))
抗原表位
65

43

20

16

15

15

11

10

9

9

8

7

6

6

5

4

3

3

3

3

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 182-211
适用
212

158

132

43

20

19

16

11

9

9

9

7

6

6

5

4

3

3

1

1

1

1

1
人
宿主
219

28

3

1

1
兔
Compatible Secondaries
克隆类型
202

50
多克隆
标记
105

17

16

14

7

7

5

5

5

5

5

5

5

5

5

5

5

3

3

3

3

3

3

2

2

2

2

2

2

1
This ERK1 antibody is un-conjugated
应用范围
200

78

67

65

65

42

39

34

30

21

18

11

7

5

3

2

1

1
Western Blotting (WB)

预测反应

D, B, M, Rat, X, E

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This MAPK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 182-211 amino acids from human MAPK3.

克隆位点

RB13301

亚型

Ig Fraction

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anti-Mitogen-Activated Protein Kinase 3 (MAPK3) (pThr185), (pThr202), (pTyr187), (pTyr204) antibody
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anti-Mitogen-Activated Protein Kinase 3 (MAPK3) (AA 279-379) antibody
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anti-Mitogen-Activated Protein Kinase 3 (MAPK3) (pThr202), (pTyr204) antibody
MAPK3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:1000

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

有效期

6 months
Tetsunaga, Nishida, Furumatsu, Naruse, Hirohata, Yoshida, Saito, Ozaki: "Regulation of mechanical stress-induced MMP-13 and ADAMTS-5 expression by RUNX-2 transcriptional factor in SW1353 chondrocyte-like cells." in: Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society, Vol. 19, Issue 2, pp. 222-32, (2011) (PubMed).

Munshi, Wu, Mukhopadhyay, Ottaviano, Sassano, Koblinski, Platanias, Stack et al.: "Differential regulation of membrane type 1-matrix metalloproteinase activity by ERK 1/2- and p38 MAPK-modulated tissue inhibitor of metalloproteinases 2 expression controls transforming growth ..." in: The Journal of biological chemistry, Vol. 279, Issue 37, pp. 39042-50, (2004) (PubMed).

Mukherjee, Huang, Petkova, Albanese, Pestell, Braunstein, Christ, Wittner, Lisanti, Berman, Weiss, Tanowitz: "Trypanosoma cruzi infection activates extracellular signal-regulated kinase in cultured endothelial and smooth muscle cells." in: Infection and immunity, Vol. 72, Issue 9, pp. 5274-82, (2004) (PubMed).

Sebkova, Pellicanò, Monteleone, Grazioli, Guarnieri, Imeneo, Pallone, Luzza: "Extracellular signal-regulated protein kinase mediates interleukin 17 (IL-17)-induced IL-8 secretion in Helicobacter pylori-infected human gastric epithelial cells." in: Infection and immunity, Vol. 72, Issue 9, pp. 5019-26, (2004) (PubMed).

Huang, Chang, Liu: "Basic fibroblast growth factor antagonizes activin A-mediated growth inhibition and hemoglobin synthesis in K562 cells by activating ERK1/2 and deactivating p38 MAP kinase." in: Biochemical and biophysical research communications, Vol. 320, Issue 4, pp. 1247-52, (2004) (PubMed).

Mizuno, Kadowaki, Demura, Ameshima, Miyamori, Ishizaki: "p42/44 Mitogen-activated protein kinase regulated by p53 and nitric oxide in human pulmonary arterial smooth muscle cells." in: American journal of respiratory cell and molecular biology, Vol. 31, Issue 2, pp. 184-92, (2004) (PubMed).
抗原

ERK1 (MAPK3) (Mitogen-Activated Protein Kinase 3 (MAPK3))

别名

MAPK3 (MAPK3 产品)

背景

MAPK3 is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets.

分子量

43136

NCBI登录号

NP_001035145, NP_001103361, NP_002737

UniProt

P27361

途径

MAPK Pathway, RTK signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, S100 Proteins