(3 references)-
- 抗原 See all Kv1.4 (KCNA4) 抗体
- Kv1.4 (KCNA4) (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 4 (KCNA4))
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抗原表位
- AA 591-619, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Kv1.4 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 预测反应
- B, M, Rat
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This KCNA4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 591-619 amino acids from the C-terminal region of human KCNA4.
- 克隆位点
- RB41939
- 亚型
- Ig Fraction
- Top Product
- Discover our top product KCNA4 Primary Antibody
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anti-Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 4 (KCNA4) (1st Extracellular Loop), (AA 348-362) antibody
KCNA4 适用: 大鼠, 小鼠 WB, IF, IHC, ICC, LCI 宿主: 兔 Polyclonal unconjugated
anti-Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 4 (KCNA4) (AA 609-647), (C-Term) antibodyKCNA4 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 4 (KCNA4) (AA 562-652) antibodyKCNA4 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 4 (KCNA4) (AA 250-350) antibodyKCNA4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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: "N-glycans modulate K(v)1.5 gating but have no effect on K(v)1.4 gating." in: Biochimica et biophysica acta, Vol. 1798, Issue 3, pp. 367-75, (2010) (PubMed).
: "Ginsenoside Rg3 inhibits human Kv1.4 channel currents by interacting with the Lys531 residue." in: Molecular pharmacology, Vol. 73, Issue 3, pp. 619-26, (2008) (PubMed).
: "Identification of an evolutionarily conserved extracellular threonine residue critical for surface expression and its potential coupling of adjacent voltage-sensing and gating domains in..." in: The Journal of biological chemistry, Vol. 283, Issue 44, pp. 30421-32, (2008) (PubMed).
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: "N-glycans modulate K(v)1.5 gating but have no effect on K(v)1.4 gating." in: Biochimica et biophysica acta, Vol. 1798, Issue 3, pp. 367-75, (2010) (PubMed).
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- 抗原
- Kv1.4 (KCNA4) (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 4 (KCNA4))
- 别名
- KCNA4 (KCNA4 产品)
- 别名
- KV1.4 antibody, KCNA4 antibody, Kv1.4 antibody, DKFZp459N0126 antibody, KCHAN antibody, Kv4 antibody, RHK1 antibody, RK3 antibody, HBK4 antibody, HK1 antibody, HPCN2 antibody, HUKII antibody, KCNA4L antibody, KCNA8 antibody, PCN2 antibody, potassium voltage-gated channel subfamily A member 4 antibody, potassium voltage-gated channel subfamily A member 4 S homeolog antibody, potassium voltage-gated channel, shaker-related subfamily, member 4 antibody, KCNA4 antibody, LOC100622932 antibody, kcna4.S antibody, Kcna4 antibody
- 背景
- Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the A-type potassium current class, the members of which may be important in the regulation of the fast repolarizing phase of action potentials in heart and thus may influnce the duration of cardiac action potential. The coding region of this gene is intronless, and the gene is clustered with genes KCNA3 and KCNA10 on chromosome 1.
- 分子量
- 73257
- NCBI登录号
- NP_002224
- UniProt
- P22459
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