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HIST2H2BE 抗体 (N-Term)

HIST2H2BE 适用: 人 WB 宿主: 兔 Polyclonal RB41930 unconjugated
产品编号 ABIN1881418
发货至: 中国
  • 抗原 See all HIST2H2BE 抗体
    HIST2H2BE (Histone H2B Type 2-E (HIST2H2BE))
    抗原表位
    • 12
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 12-40, N-Term
    适用
    • 40
    • 11
    • 11
    宿主
    • 36
    • 4
    克隆类型
    • 33
    • 7
    多克隆
    标记
    • 20
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HIST2H2BE antibody is un-conjugated
    应用范围
    • 25
    • 24
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    预测反应
    M
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This HIST2H2BE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-40 amino acids from the N-terminal region of human HIST2H2BE.
    克隆位点
    RB41930
    亚型
    Ig Fraction
    Top Product
    Discover our top product HIST2H2BE Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Kim, Guermah, McGinty, Lee, Tang, Milne, Shilatifard, Muir, Roeder: "RAD6-Mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells." in: Cell, Vol. 137, Issue 3, pp. 459-71, (2009) (PubMed).

    Pankratova, Manuĭlova, Stepchenko: "[Role of transcription factors binding sites in no-mediated histone H2B promoter repression]." in: Molekuliarnaia biologiia, Vol. 43, Issue 2, pp. 368-73, (2009) (PubMed).

    Dai, Yu, Goh, Chng, Tan, Fu, Zheng, Luo: "Histone 2B (H2B) expression is confined to a proper NAD+/NADH redox status." in: The Journal of biological chemistry, Vol. 283, Issue 40, pp. 26894-901, (2008) (PubMed).

    Zhao, Lang, Ito, Bonnet, Metzger, Sawatsubashi, Suzuki, Le Guezennec, Stunnenberg, Krasnov, Georgieva, Schüle, Takeyama, Kato, Tora, Devys: "A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing." in: Molecular cell, Vol. 29, Issue 1, pp. 92-101, (2008) (PubMed).

    Kawasaki, Schiltz, Chiu, Itakura, Taira, Nakatani, Yokoyama: "ATF-2 has intrinsic histone acetyltransferase activity which is modulated by phosphorylation." in: Nature, Vol. 405, Issue 6783, pp. 195-200, (2000) (PubMed).

  • 抗原
    HIST2H2BE (Histone H2B Type 2-E (HIST2H2BE))
    别名
    HIST2H2BE (HIST2H2BE 产品)
    别名
    RGD1562346 antibody, AV127319 antibody, H2b-613 antibody, T25626 antibody, DKFZp469C0528 antibody, H2b antibody, GL105 antibody, H2B antibody, H2B.1 antibody, H2BFQ antibody, H2BGL105 antibody, H2BQ antibody, histone cluster 2 H2B family member E antibody, histone cluster 2, H2be antibody, histone cluster 1, H2bl antibody, histone cluster 2 H2B family member e antibody, histone H2B antibody, Hist2h2be antibody, HIST2H2BE antibody, Hist1h2bl antibody, H2B antibody
    背景
    Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2B family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.
    分子量
    13920
    NCBI登录号
    NP_003519
    UniProt
    Q16778
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