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- 抗原 See all CCNDBP1 抗体
- CCNDBP1 (Cyclin D-Type Binding-Protein 1 (CCNDBP1))
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抗原表位
- AA 21-49, N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CCNDBP1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 预测反应
- Pr
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This CCNDBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-49 amino acids from the N-terminal region of human CCNDBP1.
- 克隆位点
- RB40537
- 亚型
- Ig Fraction
- Top Product
- Discover our top product CCNDBP1 Primary Antibody
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- 应用备注
- WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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A novel senescence-evasion mechanism involving Grap2 and Cyclin D interacting protein inactivation by Ras associated with diabetes in cancer cells under doxorubicin treatment." in: Cancer research, Vol. 70, Issue 11, pp. 4357-65, (2010) (PubMed).
: "Crystallization and preliminary X-ray diffraction analysis of GCIP/HHM transcriptional regulator." in: Acta crystallographica. Section F, Structural biology and crystallization communications, Vol. 65, Issue Pt 1, pp. 21-4, (2009) (PubMed).
: "An Id-like molecule, HHM, is a synexpression group-restricted regulator of TGF-beta signalling." in: The EMBO journal, Vol. 27, Issue 22, pp. 2955-65, (2008) (PubMed).
: "Immunohistochemical expression of GCIP in breast carcinoma: relationship with tumour grade, disease-free survival, mucinous differentiation and response to chemotherapy." in: Histopathology, Vol. 53, Issue 5, pp. 554-60, (2008) (PubMed).
: "Ribosomal phosphoprotein P0 interacts with GCIP and overexpression of P0 is associated with cellular proliferation in breast and liver carcinoma cells." in: Oncogene, Vol. 27, Issue 3, pp. 332-8, (2008) (PubMed).
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A novel senescence-evasion mechanism involving Grap2 and Cyclin D interacting protein inactivation by Ras associated with diabetes in cancer cells under doxorubicin treatment." in: Cancer research, Vol. 70, Issue 11, pp. 4357-65, (2010) (PubMed).
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- 抗原
- CCNDBP1 (Cyclin D-Type Binding-Protein 1 (CCNDBP1))
- 别名
- CCNDBP1 (CCNDBP1 产品)
- 别名
- CCNDBP1 antibody, dip1 antibody, gcip antibody, DIP1 antibody, GCIP antibody, HHM antibody, AU022347 antibody, Maid antibody, SECC-8 antibody, SSEC-8 antibody, cyclin D1 binding protein 1 antibody, cyclin D-type binding-protein 1 antibody, CCNDBP1 antibody, ccndbp1 antibody, Ccndbp1 antibody
- 背景
- This gene was identified by the interaction of its gene product with Grap2, a leukocyte-specific adaptor protein important for immune cell signaling. The protein encoded by this gene was shown to interact with cyclin D. Transfection of this gene in cells was reported to reduce the phosphorylation of Rb gene product by cyclin D-dependent protein kinase, and inhibit E2F1-mediated transcription activity. This protein was also found to interact with helix-loop-helix protein E12 and is thought to be a negative regulator of liver-specific gene expression. Several alternatively spliced variants have been found for this gene. [provided by RefSeq].
- 分子量
- 40262
- NCBI登录号
- NP_036274
- UniProt
- O95273
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