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Bcl-2 抗体 (AA 144-171)

This anti-Bcl-2 antibody is a 兔 多克隆 antibody detecting Bcl-2 in WB. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN1881107
发货至: 中国

Quick Overview for Bcl-2 抗体 (AA 144-171) (ABIN1881107)

抗原

See all Bcl-2 (BCL2) 抗体
Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

适用

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宿主

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克隆类型

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多克隆

标记

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This Bcl-2 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB41153
  • 抗原表位

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    AA 144-171

    预测反应

    B, C, Ha, M, Rat

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This BCL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 144-171 amino acids from the Central region of human BCL2.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Feng, Stachura, White, Gutierrez, Zhang, Sanda, Jette, Testa, Neuberg, Langenau, Kutok, Zon, Traver, Fleming, Kanki, Look: "T-lymphoblastic lymphoma cells express high levels of BCL2, S1P1, and ICAM1, leading to a blockade of tumor cell intravasation." in: Cancer cell, Vol. 18, Issue 4, pp. 353-66, (2010) (PubMed).

  • 抗原

    Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

    别名

    BCL2

    背景

    This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends. [provided by RefSeq].

    分子量

    26266

    NCBI登录号

    NP_000624

    UniProt

    P10415

    途径

    MAPK Pathway, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
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