APOBEC3A 抗体 (N-Term)
(5 references)-
- 抗原 See all APOBEC3A 抗体
- APOBEC3A (Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3A (APOBEC3A))
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抗原表位
- AA 20-49, N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This APOBEC3A antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This APOBEC3A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20-49 amino acids from the N-terminal region of human APOBEC3A.
- 克隆位点
- RB42401
- 亚型
- Ig Fraction
- Top Product
- Discover our top product APOBEC3A Primary Antibody
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anti-Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3A (APOBEC3A) (Internal Region) antibody
Verified APOBEC3A 适用: 人 ELISA, WB, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3A (APOBEC3A) (N-Term) antibodyAPOBEC3A 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3A (APOBEC3A) antibodyAPOBEC3A 适用: 人, 小鼠 ELISA, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3A (APOBEC3A) (Internal Region) antibodyAPOBEC3A 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3A (APOBEC3A) (N-Term) antibodyAPOBEC3A 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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: "Innate immune signaling induces high levels of TC-specific deaminase activity in primary monocyte-derived cells through expression of APOBEC3A isoforms." in: The Journal of biological chemistry, Vol. 285, Issue 36, pp. 27753-66, (2010) (PubMed).
: "Interaction of Vpx and apolipoprotein B mRNA-editing catalytic polypeptide 3 family member A (APOBEC3A) correlates with efficient lentivirus infection of monocytes." in: The Journal of biological chemistry, Vol. 285, Issue 16, pp. 12248-54, (2010) (PubMed).
: "APOBEC3 proteins mediate the clearance of foreign DNA from human cells." in: Nature structural & molecular biology, Vol. 17, Issue 2, pp. 222-9, (2010) (PubMed).
: "Effects of structural variations of APOBEC3A and APOBEC3B genes in chronic hepatitis B virus infection." in: Hepatology research : the official journal of the Japan Society of Hepatology, Vol. 39, Issue 12, pp. 1159-68, (2009) (PubMed).
: "APOBEC deaminases-mutases with defensive roles for immunity." in: Science in China. Series C, Life sciences / Chinese Academy of Sciences, Vol. 52, Issue 10, pp. 893-902, (2009) (PubMed).
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: "Innate immune signaling induces high levels of TC-specific deaminase activity in primary monocyte-derived cells through expression of APOBEC3A isoforms." in: The Journal of biological chemistry, Vol. 285, Issue 36, pp. 27753-66, (2010) (PubMed).
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- 抗原
- APOBEC3A (Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3A (APOBEC3A))
- 别名
- APOBEC3A (APOBEC3A 产品)
- 别名
- A3A antibody, ARP3 antibody, PHRBN antibody, bK150C2.1 antibody, APOBEC3A antibody, APOBEC3Z1 antibody, apolipoprotein B mRNA editing enzyme catalytic subunit 3A antibody, apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A antibody, apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3Z1 antibody, similar to ARP10 protein antibody, APOBEC3A antibody, APOBEC3Z1 antibody
- 背景
- This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. The protein encoded by this gene lacks the zinc binding activity of other family members. The protein plays a role in immunity, by restricting transmission of foreign DNA such as viruses. One mechanism of foreign DNA restriction is deamination of foreign double-stranded DNA cytidines to uridines, which leads to DNA degradation. However, other mechanisms are also thought to be involved, as anti-viral effect is not dependent on deaminase activity. One allele of this gene results from the deletion of approximately 29.5 kb of sequence between this gene, APOBEC3A, and the adjacent gene APOBEC3B. The breakpoints of the deletion are within the two genes, so the deletion allele is predicted to have the promoter and coding region of APOBEC3A, but the 3' UTR of APOBEC3B.
- 分子量
- 23012
- NCBI登录号
- NP_001180218, NP_663745
- UniProt
- P31941
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