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Caspase 8 抗体 (N-Term)

CASP8 适用: 人 WB 宿主: 小鼠 Monoclonal FLICE-1 unconjugated
产品编号 ABIN187519
发货至: 中国
  • 抗原 See all Caspase 8 (CASP8) 抗体
    Caspase 8 (CASP8)
    抗原表位
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    N-Term
    适用
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    宿主
    • 126
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    小鼠
    克隆类型
    • 125
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    单克隆
    标记
    • 90
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    This Caspase 8 antibody is un-conjugated
    应用范围
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    Western Blotting (WB)
    过滤
    0.2 μm filtered
    免疫原
    Recombinant human caspase-8.
    克隆位点
    FLICE-1
    亚型
    IgG1
    Top Product
    Discover our top product CASP8 Primary Antibody
  • 应用备注
    Western Blot The optimal dilution for a specific application should be determined by the researcher.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Mouse monoclonal antibody against human Caspase-8 (cysteine-requiring aspartate protease-8). Available in 100 µl vials at a concentration of 1 mg/ml (100 µg) in PBS with 0.08% sodium azide. Antibody was purified by 0.2 µm sterile filtration.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • 抗原
    Caspase 8 (CASP8)
    别名
    Caspase-8 (CASP8 产品)
    别名
    casp8-A antibody, xCaspase-8 antibody, casp8 antibody, CASP8 antibody, CASP-8 antibody, FLICE antibody, MACH antibody, Mch5 antibody, ALPS2B antibody, CAP4 antibody, Casp-8 antibody, MCH5 antibody, caspase-8 antibody, zgc:92075 antibody, caspase 8 L homeolog antibody, death related ced-3/Nedd2-like protein antibody, caspase 8 antibody, caspase-8 antibody, caspase-8-like antibody, caspase 8, apoptosis-related cysteine peptidase antibody, casp8.L antibody, LOC661095 antibody, CASP8 antibody, LOC5563818 antibody, casp8 antibody, LOC100222284 antibody, Casp8 antibody
    背景
    Caspases are key effectors of programmed cell death. They are synthesized as inactive pro-enzymes, which are activated by cleavage at a specific aspartate residue to form two subunits. These subunits are normally linked together by a linker, which may be involved in the regulation of the different caspases. Caspase-8 is a key enzyme in the apoptosis pathway. Caspase-8 contains two N-terminal region death effector domains, which are removed to activate the enzyme along with cleavage in the two subunits. These subunits then form the active protease, which is capable of cleaving caspase-3, -6 and -7. These caspases are then capable of cleaving other cellular substrates such as PARP and DFF, which in turn induce apoptosis.
    途径
    Apoptosis, Caspase Cascade in Apoptosis, TLR signaling, Activation of Innate immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades
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