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Desmoglein 1 抗体

DSG1 适用: 人 WB, IF, IP, IHC (fro) 宿主: 小鼠 Monoclonal 27B2 unconjugated
产品编号 ABIN187347
发货至: 中国
  • 抗原 See all Desmoglein 1 (DSG1) 抗体
    Desmoglein 1 (DSG1)
    适用
    • 86
    • 23
    • 11
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 56
    • 30
    • 1
    小鼠
    克隆类型
    • 51
    • 36
    单克隆
    标记
    • 38
    • 9
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    This Desmoglein 1 antibody is un-conjugated
    应用范围
    • 48
    • 27
    • 27
    • 21
    • 20
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    The antibody reacts with the 165 kDa desmoglein 1 protein. Furthermore it does NOT cross-react with desmoglein 2 or desmolglein 3. Clone 27B2 does NOT inhibit the biological activity of desmolein 1. Species Reactivity: Human. Others not tested.
    过滤
    0.2 μm filtered
    克隆位点
    27B2
    亚型
    IgG1
    Top Product
    Discover our top product DSG1 Primary Antibody
  • 应用备注
    Immunofluorescence: Use at a 1:10 dilution. Immunohistology: frozen sections Immunoprecipitation: Use at a 1:10 dilution. Western blotting The optimal dilution for a specific application should be determined by the researcher.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    1 mL at 100 µg/mL of 0.2 µm filtered antibody solution in PBS, containing 0.02% sodium azide and 0.1% protein stabilizer.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
  • 抗原
    Desmoglein 1 (DSG1)
    别名
    Desmoglein-1 (DSG1 产品)
    别名
    CDHF4 antibody, DG1 antibody, DSG antibody, PPKS1 antibody, SPPK1 antibody, DSG-1 antibody, DSG1 antibody, Dsg1b antibody, Dsg1c antibody, desmoglein 1 antibody, desmoglein 4 antibody, DSG1 antibody, DSG4 antibody, Dsg1 antibody
    背景
    Desmoglein 1 is a member of the desmosomal cadherin family that comprise the desmogleins and desmocollins. Desmosomes are cell-cell junctions in most epithelial cells and serve to link the intermediate filament cytoskeletons of adjacent cells. Within the desmosome the extracellular domain of desmoglein is essential for calcium dependent heterophilic binding to the desmocollins, whereas the intracellular domain is essential for binding to the desmosomal plaque protein, plakoglobin. Desmoglein 1 is synthesized exclusively in the suprabasal layers. Intact and functionally active desmolgein 1 is essential to epidermal integrity.
    途径
    Cell-Cell Junction Organization
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