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Lipoprotein Lipase 抗体 (AA 380-410)

LPL 适用: 人, 大鼠, Cow, Pig, 豚鼠, 小鸡 WB, ELISA, IP, Func 宿主: 小鼠 Monoclonal 5D2 unconjugated
产品编号 ABIN1820143
发货至: 中国
  • 抗原 See all Lipoprotein Lipase (LPL) 抗体
    Lipoprotein Lipase (LPL)
    抗原表位
    • 16
    • 9
    • 7
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 380-410
    适用
    • 72
    • 27
    • 22
    • 15
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, Cow, Pig, 豚鼠, 小鸡
    宿主
    • 60
    • 16
    • 2
    小鼠
    克隆类型
    • 55
    • 24
    单克隆
    标记
    • 35
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Lipoprotein Lipase antibody is un-conjugated
    应用范围
    • 62
    • 32
    • 32
    • 23
    • 14
    • 14
    • 14
    • 8
    • 7
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunoprecipitation (IP), Functional Studies (Func)
    特异性
    Recognizes an epitope within amino acids 380-410 of lipoprotein lipase (LPL), a member of the AB hydrolase superfamily, which plays a pivotal role in lipoprotein metabolism and transport, acting as the key enzyme in the hydrolysis of triglycerides and very low density lipoproteins (VLDLs), and the release of free fatty acids into peripheral tissues. A deficiency of LPL can result in hypertriglyceridemia, and many studies have focused on the critical role which LPL plays in the pathogenesis of atherosclerosis, and in particular the relationship between LPL and apolipoprotein E (ApoE), both of which are secreted in significant amounts by macrophages in developing arterial wall lesions. Clone 5D2 is a unique antibody which differentiates between monomeric inactive and dimeric active LPL, and binds to LPL sequences involved in LPL, LPL receptor, and heparin interactions. Clone 5D2 has been shown to inhibit the activity of human LPL(2,3), and is widely used in human studies.
    无交叉反应
    小鼠
    纯化方法
    Protein G purified
    内毒素水平
    Low Endotoxin
    免疫原
    Purified bovine milk lipoprotein lipase.

    Type of Immunogen: Purified protein
    克隆位点
    5D2
    亚型
    IgG1
    Top Product
    Discover our top product LPL Primary Antibody
  • 应用备注
    Approved: ELISA (1:500 - 1:5000), Func, IP, WB

    Usage: The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.
    说明

    Target Species of Antibody: Bovine

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    PBS
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze-thaw cycles.
  • 抗原
    Lipoprotein Lipase (LPL)
    别名
    Lipoprotein Lipase / LPL (LPL 产品)
    别名
    HDLCQ11 antibody, LIPD antibody, fb62e04 antibody, fc49b03 antibody, wu:fb62e04 antibody, wu:fc49b03 antibody, LPL antibody, lipd antibody, hdlcq11 antibody, lpl antibody, LOC100223817 antibody, lipoprotein lipase antibody, LPL antibody, Lpl antibody, lpl antibody
    背景
    Name/Gene ID: LPL

    Synonyms: LPL, LIPD, Lipoprotein lipase, HDLCQ11
    基因ID
    4023
    途径
    Lipid Metabolism
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