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MMP1 抗体 (C-Term)

MMP1 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 3B6 unconjugated
产品编号 ABIN1819904
发货至: 中国
  • 抗原 See all MMP1 抗体
    MMP1 (Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1))
    抗原表位
    • 15
    • 15
    • 15
    • 7
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    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 4
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    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 118
    • 54
    • 50
    • 35
    • 16
    • 5
    • 4
    • 3
    • 1
    • 1
    宿主
    • 104
    • 20
    • 1
    小鼠
    克隆类型
    • 108
    • 17
    单克隆
    标记
    • 55
    • 13
    • 10
    • 10
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
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    • 2
    This MMP1 antibody is un-conjugated
    应用范围
    • 110
    • 57
    • 39
    • 39
    • 37
    • 25
    • 21
    • 14
    • 11
    • 5
    • 3
    • 3
    • 2
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    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    Recognizes human matrix metalloproteinase 1 (MMP-1). The MMPs are zinc-dependent endopeptidases responsible for degrading the extracellular matrix. They are also involved in cell proliferation, migration, differentiation and apoptosis. Most MMPs are synthesized as inactive zymogens and a propeptide region must be cleaved off before the enzyme becomes active. Their expression is increased dramatically in a variety of cancer types, where it indicates invasive disease and a poor prognosis. MMP-1 is one of the collagenases, capable of degrading collagens I, II and III, all main components of the interstitial stroma. It is overexpressed in invasive melanoma, colorectal and esophageal cancers. It has also been implicated in arthritis and might influence atherosclerotic lesion formation. It might also be involved in the repair processes of the heart after myocardial infarction.
    纯化方法
    Protein G purified
    免疫原
    Ovalbumin conjugated synthetic peptide corresponding to a region within the C-terminus of human MMP-1.

    Type of Immunogen: Synthetic peptide
    克隆位点
    3B6
    亚型
    IgG1
    Top Product
    Discover our top product MMP1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    说明

    Target Species of Antibody: Human

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    PBS, 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    4°C or -20°C, Avoid freeze-thaw cycles.
  • 抗原
    MMP1 (Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1))
    别名
    MMP1 (MMP1 产品)
    别名
    CLG antibody, CLGN antibody, Mmp1a antibody, CG4859 antibody, Dm1-MMP antibody, Dmel\\CG4859 antibody, MMP-1 antibody, MMP1 antibody, Mmp 1 antibody, dMMP1 antibody, dm1-MMP antibody, dmmp1 antibody, l(2)k04809 antibody, mmp1 antibody, Mmp1 antibody, Mcol-A antibody, Mcola antibody, col4 antibody, mmp18 antibody, Clgn antibody, matrix metallopeptidase 1 antibody, Matrix metalloproteinase 1 antibody, matrix metalloproteinase 1 antibody, matrix metallopeptidase 1 (interstitial collagenase) antibody, matrix metallopeptidase 1a (interstitial collagenase) antibody, matrix metallopeptidase 1 S homeolog antibody, interstitial collagenase antibody, matrix metallopeptidase 8 L homeolog antibody, MMP1 antibody, Mmp1 antibody, RB11133 antibody, Mmp1a antibody, mmp1.S antibody, LOC100727966 antibody, mmp8.L antibody
    背景
    Name/Gene ID: MMP1
    Subfamily: Metallopeptidase M10A
    Family: Protease

    Synonyms: MMP1, CLG, Fibroblast collagenase, Matrix metalloprotease 1, MMP-1, Interstitial collagenase, Matrix metalloproteinase 1, Matrix metalloproteinase-1
    基因ID
    4312
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