EPOR 抗体 (Extracellular Domain)
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- 抗原 See all EPOR 抗体
- EPOR (Erythropoietin Receptor (EPOR))
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抗原表位
- Extracellular Domain
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适用
- 人, 小鼠
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宿主
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绵羊
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克隆类型
- 多克隆
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标记
- This EPOR antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunoprecipitation (IP)
- 特异性
- Recognizes Erythropoietin Receptor (EPOR), a type I transmembrane protein and member of the type I cytokine receptor family, expressed by erythroid cells and erythroid progenitor cells, which acts as a receptor for erythropoietin (EPO) to mediate erythroblast proliferation and differentiation, and maintain progenitor survival. Binding of EPO to EPOR, results in the dimerization of the EPOR and the triggering of the JAK2/STAT5 signaling cascade, and in some cell types activation of STAT1 and STAT3. Several isoforms of EPOR exist: EPOR-F, EPOR-S and EPOR-T, and a functional EPOR is found on endothelial cells and cardiomyocytes within the cardiovascular system, suggesting a role in cardiac function. AHP1825 has been shown to block Iodine125 labeled erythropoietin ligand binding using erythroleukemia cell line TF-1 with 3000 EPOR/cell in neutralization studies, see for details. AHP1825 is reported as suitable for use in immunocytochemistry. AHP1825 has been reported for use in functional studies. Removal of Sodium Azide is recommended prior to use in functional assays. The recommended concentration for functional assays is 500 μg/mL.
- 纯化方法
- Affinity purified
- 免疫原
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Partial cDNA of the extracellular domain of human EpoR expressed as a GST fusion protein in E. coli.
Type of Immunogen: Fusion protein - 亚型
- IgG
- Top Product
- Discover our top product EPOR Primary Antibody
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anti-Erythropoietin Receptor (EPOR) (AA 31-130) antibody
EPOR 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 3D10 unconjugated
anti-Erythropoietin Receptor (EPOR) (AA 301-450) antibodyEPOR 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Erythropoietin Receptor (EPOR) (AA 470-504), (C-Term) antibodyEPOR 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB50846 unconjugated
anti-Erythropoietin Receptor (EPOR) (AA 45-244) antibodyEPOR 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Erythropoietin Receptor (EPOR) (AA 31-130) antibodyEPOR 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3F6 unconjugated
anti-Erythropoietin Receptor (EPOR) (AA 274-508) antibodyEPOR 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Erythropoietin Receptor (EPOR) (AA 320-506) antibodyEPOR 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Erythropoietin Receptor (EPOR) antibodyEPOR 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Erythropoietin Receptor (EPOR) antibodyEPOR 适用: 人 FACS, cELISA 宿主: 小鼠 Monoclonal VP-2E8 unconjugated
anti-Erythropoietin Receptor (EPOR) antibodyEPOR 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Approved: ELISA, IP (10 μg/mL), WB (10 μg/mL)
- 说明
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Target Species of Antibody: Human
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- PBS, 0.09 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Do not freeze.
- 储存条件
- 4 °C
- 储存方法
- Store at 4°C. Do not freeze.
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- 抗原
- EPOR (Erythropoietin Receptor (EPOR))
- 别名
- EPOR / EPO Receptor (EPOR 产品)
- 别名
- EPOR antibody, epor antibody, EPO-R antibody, erythropoietin receptor antibody, erythropoietin receptor L homeolog antibody, EPOR antibody, epor antibody, Epor antibody, epor.L antibody
- 背景
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Name/Gene ID: EPOR
Family: Cytokine Receptor
Synonyms: EPOR, EPO Receptor, EPO-R, Erythropoietin receptor - 基因ID
- 2057
- 途径
- JAK/STAT Signaling
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