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CD14 抗体

CD14 适用: 人, Cow, 绵羊, Water Buffalo FACS, IF 宿主: 小鼠 Monoclonal CC-G33 unconjugated
产品编号 ABIN1819121
发货至: 中国
  • 抗原 See all CD14 抗体
    CD14
    适用
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    人, Cow, 绵羊, Water Buffalo
    宿主
    • 198
    • 54
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD14 antibody is un-conjugated
    应用范围
    • 202
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    Flow Cytometry (FACS), Immunofluorescence (IF)
    特异性
    Recognizing bovine CD14, a GPI-anchored membrane glycoprotein and monocyte/macrophage differentiation antigen, belonging to the lipopolysaccharide receptor family, also expressed weakly on microglia and Langerhans cells. CD14 acts as a receptor for the potent bacterial endotoxin, lipopolysaccharide (LPS), facilitated by LPS-binding protein (LBP). The binding of LPS to CD14 results in cell activation and the release of cytokines and the inflammatory response, and has been shown to upregulate the cell surface expression of adhesion molecules. Cross-reacts with human CD14 expressed on transfected COS-7 cells, and also recognizes an epitope on ovine CD14, see for details. CC-G33 has also been shown to be reactive with CD14 from the Water buffalo.
    纯化方法
    Protein G purified
    免疫原
    Partially purified polypeptides isolated from bovine leucocyte cell surface membrane.

    Type of Immunogen: Purified protein
    克隆位点
    CC-G33
    亚型
    IgG1
    Top Product
    Discover our top product CD14 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    说明

    Target Species of Antibody: Bovine

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    PBS, 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C,-20 °C
    储存方法
    4°C or -20°C, Avoid freeze-thaw cycles.
  • 抗原
    CD14
    别名
    CD14 (CD14 产品)
    背景
    Name/Gene ID: CD14

    Synonyms: CD14, CD14 Molecule, CD14 antigen
    基因ID
    929
    UniProt
    P08571
    途径
    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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