C1QA 抗体
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北京 101111
Quick Overview for C1QA 抗体 (ABIN181104)
抗原
See all C1QA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody recognises human complement component 1, q subcomponent (C1q), a 156 kDa secreted protein.
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交叉反应 （详细）
- Species reactivity (tested):Human.
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产品特性
- Synonyms: Complement C1q, Complement 1q
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纯化方法
- Affinity Chromatography on Protein A.
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免疫原
- Binds globular head domain of C1q, purified from human plasma. Genename: C1QA, C1QB, C1QC
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亚型
- IgG1
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anti-Complement Component 1, Q Subcomponent, A Chain (C1QA) (AA 23-245) antibody
C1QA 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 1, Q Subcomponent, A Chain (C1QA) (AA 23-167) antibodyC1QA 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 8B5B1 unconjugated
anti-Complement Component 1, Q Subcomponent, A Chain (C1QA) (AA 28-245) antibodyC1QA 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 1, Q Subcomponent, A Chain (C1QA) (AA 23-167) antibodyC1QA 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 1C7G3 unconjugated
anti-Complement Component 1, Q Subcomponent, A Chain (C1QA) (AA 104-237) antibodyC1QA 适用: 人 WB, ELISA, Coat 宿主: 小鼠 Monoclonal C1QA-2783 unconjugated
anti-Complement Component 1, Q Subcomponent, A Chain (C1QA) (AA 104-237) antibodyC1QA 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal C1QA-2952 unconjugated
anti-Complement Component 1, Q Subcomponent, A Chain (C1QA) (AA 96-245) antibodyC1QA 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 1C9G9 unconjugated
anti-Complement Component 1, Q Subcomponent, A Chain (C1QA) (AA 26-125) antibodyC1QA 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 1, Q Subcomponent, A Chain (C1QA) (AA 1-245) antibodyC1QA 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 1, Q Subcomponent, A Chain (C1QA) (AA 23-245) antibodyC1QA 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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ELISA. Flow Cytometry. Immunohistochemistry on Frozen Sections: It has been reported that this antibody worksvery well on acetone-fixed, frozen renal biopsies at a dilution of 1/500-1/600. Strongstaining was observed in the glomeruli and in some cases the peritubular capillary(potentially clinically significant). Recommended Positive Control: Kidney tissue from patients with streptococalglomerulonephritis.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- Borate Buffered Saline, pH 8.4 containing 0.02 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- C1QA (Complement Component 1, Q Subcomponent, A Chain (C1QA))
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别名
- C1q A Subunit
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背景
- C1q associates with proenzymes C1r and C1s to form the calcium-dependent C1 complex, the first component of the serum complement system. C1q is composed of six A, six B-chains and six C-polypeptide chains. Each chain contains a collagen-like region located near the N-terminus and a C-terminal globular region. These regions bind the Fc region of IgM and IgG molecules, initiating the classical pathway of complement activation. C1q deficiency has been associated with lupus erythematosus and glomerulonephritis.Synonyms: Complement 1q, Complement C1q
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基因ID
- 712
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UniProt
- P02745
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途径
- Complement System
抗原
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