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CLEC10A 抗体 (Biotin)

CLEC10A 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal ER-MP23 Biotin
产品编号 ABIN181063
发货至: 中国
  • 抗原 See all CLEC10A 抗体
    CLEC10A (C-Type Lectin Domain Family 10, Member A (CLEC10A))
    适用
    • 29
    • 10
    小鼠
    宿主
    • 30
    • 4
    • 4
    • 1
    大鼠
    克隆类型
    • 33
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    单克隆
    标记
    • 18
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    This CLEC10A antibody is conjugated to Biotin
    应用范围
    • 24
    • 23
    • 16
    • 6
    • 3
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    Flow Cytometry (FACS)
    特异性
    This antibody recognises the CD301 cell surface protein. In mice, CD301 is predominantly expressed on mature macrophages found associated with a wide range of connective tissues including macrophages in the dermis and the pancreas. Clone ER-MP23 also detects a population of dendritic cells in lymphoid tissue, which are probably recent immigrants from peripheral connective tissue sites. Clone ER-MP23 is reported to block the function of murine CD301. The antibody binds both MGL1 and MGL2 homologues.
    产品特性
    Synonyms: CLECSF13, CLECSF14, HML, C-type lectin domain family 10 member A, C-type lectinsuperfamily member 14, Macrophage lectin 2
    纯化方法
    Affinity Chromatography on Protein G
    免疫原
    Balb/c macrophage precursor cell hybrids. Cells from immunised rats were fused with cells of the rat Y3-Ag1. 2. 3 myeloma cell line.
    克隆位点
    ER-MP23
    亚型
    IgG2a
    Top Product
    Discover our top product CLEC10A Primary Antibody
  • 应用备注
    Flow Cytometry: Use 10 μL of Neat-1/10 diluted antibody to label 10^6 cells in 100 μL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.1 mg/mL
    缓冲液
    PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    有效期
    12 months
  • Lederle, Hartenstein, Meides, Kunzelmann, Werb, Angel, Mueller: "MMP13 as a stromal mediator in controlling persistent angiogenesis in skin carcinoma." in: Carcinogenesis, Vol. 31, Issue 7, pp. 1175-84, (2010) (PubMed).

  • 抗原
    CLEC10A (C-Type Lectin Domain Family 10, Member A (CLEC10A))
    别名
    CD301 / CLEC10A (CLEC10A 产品)
    别名
    CLEC10A antibody, CD301 antibody, CLECSF13 antibody, CLECSF14 antibody, HML antibody, HML2 antibody, MGL antibody, CD301a antibody, M-ASGP-BP-1 antibody, Mgl antibody, Mgl1 antibody, Mgll antibody, C-type lectin domain family 10 member A antibody, C-type lectin domain containing 10A antibody, C-type lectin domain family 10, member A antibody, LOC607405 antibody, CLEC10A antibody, Clec10a antibody
    背景
    In mice, CD301 is predominantly expressed on mature macrophages found associated with a wide range of connective tissues including macrophages in the dermis and the pancreas. Clone ER-MP23 also detects a population of dendritic cells in lymphoid tissue, which are probably recent immigrants from peripheral connective tissue sites. Expression of CD301 is induced by alternative (i.e. IL-4/IL-13 mediated) activation of macrophages and dendritic cells, but not all CD301 positive cells are necessarily IL-4/IL-13 stimulated.Synonyms: C-type lectin domain family 10 member A, C-type lectin superfamily member 14, CLECSF13, CLECSF14, HML, Macrophage lectin 2
    基因ID
    10462
    UniProt
    Q8IUN9
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